Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2022869..2023140 Replicon chromosome
Accession NZ_CP074042
Organism Escherichia coli strain PI6

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2022999..2023102 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2022869..2023140 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFU63_RS09755 2019424..2020086 - 663 WP_000944256.1 exodeoxyribonuclease X -
KFU63_RS09760 2020110..2020766 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
KFU63_RS09765 2020868..2021098 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KFU63_RS09770 2021237..2021611 + 375 WP_000204699.1 CopC domain-containing protein YobA -
KFU63_RS09775 2021615..2022487 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
KFU63_RS09780 2022500..2022841 + 342 WP_000976472.1 YebY family protein -
- 2022869..2023140 - 272 - - Antitoxin
- 2022999..2023102 + 104 - - Toxin
KFU63_RS09785 2023237..2023893 + 657 WP_000812710.1 protein-serine/threonine phosphatase -
KFU63_RS09790 2023894..2024085 - 192 WP_001296140.1 YebW family protein -
KFU63_RS09795 2024190..2024426 - 237 WP_001295499.1 YebV family protein -
KFU63_RS09800 2024544..2025983 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T201266 NZ_CP074042:2022999-2023102 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT201266 NZ_CP074042:c2023140-2022869 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References