20126

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 2085826..2086211 Replicon chromosome
Accession NC_000911
Organism Synechocystis sp. PCC 6803

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SGL_RS18935 Protein ID WP_080504056.1
Coordinates 2086107..2086211 (+) Length 35 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag SGL_RS11730 Protein ID WP_010873096.1
Coordinates 2085826..2086110 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SGL_RS11695 (slr0442) 2080885..2082720 + 1836 WP_010873091.1 hypothetical protein -
SGL_RS11700 (sll0428) 2082864..2083916 - 1053 WP_010873092.1 2OG-Fe(II) oxygenase -
SGL_RS11705 2084143..2084370 + 228 WP_020862282.1 DUF2281 domain-containing protein -
SGL_RS18930 2084416..2084760 + 345 WP_071822655.1 type II toxin-antitoxin system VapC family toxin -
SGL_RS11715 2084922..2085206 + 285 WP_014407120.1 BrnT family toxin -
SGL_RS11720 (slr1005) 2085211..2085417 + 207 WP_010873094.1 hypothetical protein -
SGL_RS11725 (ssr0759) 2085445..2085684 + 240 WP_010873095.1 hypothetical protein -
SGL_RS11730 (ssr0761) 2085826..2086110 + 285 WP_010873096.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
SGL_RS18935 2086107..2086211 + 105 WP_080504056.1 type II toxin-antitoxin system YoeB family toxin Toxin
SGL_RS11735 (sll0427) 2086305..2087129 - 825 WP_010873097.1 photosystem II manganese-stabilizing polypeptide -
SGL_RS11740 (slr0443) 2087356..2087733 + 378 WP_010873098.1 hypothetical protein -
SGL_RS11750 (sll0426) 2088130..2088492 - 363 WP_010873099.1 hypothetical protein -
SGL_RS11755 (slr0444) 2088680..2090023 + 1344 WP_010873100.1 3-phosphoshikimate 1-carboxyvinyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-32)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(19-83)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 4196.90 Da        Isoelectric Point: 8.5633

>T20126 WP_080504056.1 NC_000911:2086107-2086211 [Synechocystis sp. PCC 6803]
VKLIFSEQAWSDYLYWQQNDKKILKRINTLVELI

Download         Length: 105 bp

>T20126 NC_000911:2086107-2086211 [Synechocystis sp. PCC 6803]
GTGAAGCTAATTTTCTCTGAGCAAGCCTGGAGCGATTATCTTTACTGGCAACAAAACGACAAGAAAATACTTAAAAGAAT
CAATACCTTAGTTGAATTAATTTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10540.02 Da        Isoelectric Point: 4.1364

>AT20126 WP_010873096.1 NC_000911:2085826-2086110 [Synechocystis sp. PCC 6803]
MGETLPQQLPNMNAVSQIIAQQKLAAIMEQVCSDHVPTIITRDTQPSVVMISLEDYQSLEETAYLLRSPNNAQKLMSAIK
QLENDQGVERELLE

Download         Length: 285 bp

>AT20126 NC_000911:2085826-2086110 [Synechocystis sp. PCC 6803]
ATGGGGGAAACTTTGCCCCAACAATTGCCAAACATGAACGCAGTCAGCCAAATTATTGCACAACAAAAACTTGCAGCTAT
CATGGAGCAAGTATGTAGTGATCATGTTCCAACAATTATCACCAGGGATACCCAACCATCTGTCGTCATGATTTCCCTGG
AAGACTATCAGTCATTAGAAGAAACAGCATATCTACTACGTAGCCCGAACAATGCTCAAAAATTGATGTCGGCGATCAAG
CAATTAGAAAATGATCAAGGTGTCGAAAGGGAACTATTGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References