20124

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1660069..1660711 Replicon chromosome
Accession NC_000911
Organism Synechocystis sp. PCC 6803

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SGL_RS09675 Protein ID WP_010872706.1
Coordinates 1660277..1660711 (+) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SGL_RS09670 Protein ID WP_010872705.1
Coordinates 1660069..1660287 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SGL_RS09655 (sll1236) 1655289..1655672 - 384 WP_010872702.1 heterocyst frequency control protein PatD -
SGL_RS09660 (slr1325) 1656043..1658325 + 2283 WP_010872703.1 RelA/SpoT family protein -
SGL_RS09665 (sll1234) 1658511..1659788 - 1278 WP_010872704.1 adenosylhomocysteinase -
SGL_RS09670 (ssr2201) 1660069..1660287 + 219 WP_010872705.1 hypothetical protein Antitoxin
SGL_RS09675 (slr1327) 1660277..1660711 + 435 WP_010872706.1 putative toxin-antitoxin system toxin component, PIN family Toxin
SGL_RS09680 (sll1233) 1660739..1661623 - 885 WP_010872707.1 transglutaminase family protein -
SGL_RS09685 (sll1232) 1661722..1662285 - 564 WP_010872708.1 Uma2 family endonuclease -
SGL_RS09690 (sll1231) 1662306..1663505 - 1200 WP_010872709.1 glycosyltransferase family 4 protein -
SGL_RS09695 (sll1229) 1663554..1664690 - 1137 WP_010872710.1 hybrid sensor histidine kinase/response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 16459.94 Da        Isoelectric Point: 4.4099

>T20124 WP_010872706.1 NC_000911:1660277-1660711 [Synechocystis sp. PCC 6803]
MNNEVIRVVIDTNIWISFLIGKTLQGLNQAIIDNQVVILFSDTLFTELMEVLHHPKFKKYFSGTAIQNLIALLNEKVELV
EVNLHFDSYRDKKDNFLLDLAVSGNANYLVTGDSDLLTLNPFDNVEIISYQHFQAIILAMMDNQ

Download         Length: 435 bp

>T20124 NC_000911:1660277-1660711 [Synechocystis sp. PCC 6803]
ATGAACAATGAAGTTATCCGGGTTGTAATTGATACGAATATCTGGATCAGTTTTCTAATTGGAAAAACTCTTCAAGGTTT
AAATCAAGCCATCATTGATAACCAAGTGGTCATTTTATTCAGTGACACTTTGTTTACTGAGCTGATGGAAGTATTACACC
ATCCTAAATTCAAAAAGTACTTTTCCGGAACAGCCATCCAAAATTTAATCGCACTGTTAAACGAAAAAGTTGAATTGGTT
GAAGTGAATCTTCATTTTGACAGTTATCGAGACAAAAAAGATAATTTCTTGCTGGATTTGGCAGTCTCAGGCAATGCAAA
TTATTTGGTGACGGGAGATAGTGACCTATTGACATTAAACCCATTTGACAATGTAGAAATTATCTCCTATCAACATTTTC
AAGCTATTATTTTAGCCATGATGGATAATCAGTAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8400.43 Da        Isoelectric Point: 4.2583

>AT20124 WP_010872705.1 NC_000911:1660069-1660287 [Synechocystis sp. PCC 6803]
MHSLSSLEFPELKSVIAQCNLEEKLELLELLEKDTFGTRFNKFLNSVKTDELTLEDITQEVESVRQANYHEQ

Download         Length: 219 bp

>AT20124 NC_000911:1660069-1660287 [Synechocystis sp. PCC 6803]
ATGCACTCATTGTCATCACTGGAATTTCCTGAGCTTAAAAGTGTTATTGCCCAATGTAATCTTGAAGAAAAACTTGAATT
ATTAGAACTTTTGGAAAAGGATACTTTTGGCACCAGATTTAACAAATTTTTAAATTCTGTCAAAACTGACGAATTAACCT
TAGAAGACATTACACAAGAAGTTGAATCGGTCCGGCAAGCTAATTATCATGAACAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References