Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2030745..2031016 Replicon chromosome
Accession NZ_CP074024
Organism Escherichia coli strain PK5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2030875..2030978 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2030745..2031016 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFU66_RS09905 2027300..2027962 - 663 WP_000944258.1 exodeoxyribonuclease X -
KFU66_RS09910 2027986..2028642 - 657 WP_219370993.1 carbon-nitrogen hydrolase family protein YobB -
KFU66_RS09915 2028744..2028974 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KFU66_RS09920 2029113..2029487 + 375 WP_000168747.1 CopC domain-containing protein YobA -
KFU66_RS09925 2029491..2030363 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
KFU66_RS09930 2030376..2030717 + 342 WP_000976472.1 YebY family protein -
- 2030745..2031016 - 272 - - Antitoxin
- 2030875..2030978 + 104 - - Toxin
KFU66_RS09935 2031113..2031769 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
KFU66_RS09940 2031770..2031961 - 192 WP_001338167.1 YebW family protein -
KFU66_RS09945 2032066..2032302 - 237 WP_001338166.1 YebV family protein -
KFU66_RS09950 2032421..2033860 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T201144 NZ_CP074024:2030875-2030978 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT201144 NZ_CP074024:c2031016-2030745 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References