Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) abiEi-abiEii/AbiEii(toxin)
Location 1523693..1524862 Replicon chromosome
Accession NC_000868
Organism Pyrococcus abyssi GE5

Toxin (Protein)


Gene name PygT Uniprot ID -
Locus tag PAB_RS08445 Protein ID WP_052320089.1
Coordinates 1524296..1524862 (+) Length 189 a.a.

Antitoxin (Protein)


Gene name PygA Uniprot ID -
Locus tag PAB_RS08440 Protein ID WP_010868683.1
Coordinates 1523693..1524154 (+) Length 154 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAB_RS08410 (PAB1029) 1519091..1520035 + 945 WP_010868678.1 calcium/sodium antiporter -
PAB_RS08415 (PAB1030) 1520048..1520722 + 675 WP_010868679.1 hypothetical protein -
PAB_RS08420 (PAB1325) 1520682..1521116 - 435 WP_048147078.1 NfeD family protein -
PAB_RS08425 (PAB1324) 1521122..1522018 - 897 WP_048147080.1 SPFH domain-containing protein -
PAB_RS10235 (PAB1031) 1523074..1523418 + 345 WP_231845542.1 hypothetical protein -
PAB_RS08440 (PAB1032) 1523693..1524154 + 462 WP_010868683.1 hypothetical protein Antitoxin
PAB_RS08445 (PAB1033) 1524296..1524862 + 567 WP_052320089.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
PAB_RS08450 1524878..1525087 + 210 WP_048147085.1 hypothetical protein -
PAB_RS08455 (PAB1035) 1525638..1527188 + 1551 WP_010868685.1 ribonuclease J -
PAB_RS08460 (PAB1036) 1527250..1528272 + 1023 WP_010868686.1 hypothetical protein -
PAB_RS10045 (PAB1037) 1528283..1528909 + 627 WP_010868687.1 class II glutamine amidotransferase -
PAB_RS10270 1528938..1529006 + 69 Protein_1671 hypothetical protein -
PAB_RS10240 1529007..1529261 + 255 WP_231845594.1 hypothetical protein -
PAB_RS08470 1529346..1529540 + 195 WP_231845543.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(3-182)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 189 a.a.        Molecular weight: 22493.84 Da        Isoelectric Point: 5.8121

>T20113 WP_052320089.1 NC_000868:1524296-1524862 [Pyrococcus abyssi GE5]
MIKCYLSYYRFSVDLDFTFPLRNRLSRSGRRKLISSEVRWLSEKLSYIAEELGLNFRPFEGNSYDRNFVHFEGNENRKIV
FFHLFMPTGEVVKIEVNFFEPVLFEEKKVLAKTLLDGVKLEDEEKTYFFEELERYLTLSVTAYSPEEILAEKIRAILTRR
IQKLRDFYDVFMLHKAGYDYSNVIDEAL

Download         Length: 567 bp

>T20113 NC_000868:1524296-1524862 [Pyrococcus abyssi GE5]
TTGATAAAGTGTTACCTCAGCTATTACCGCTTCAGTGTTGACCTTGACTTCACGTTCCCACTGAGGAACAGGCTCTCCCG
CTCGGGGAGGAGAAAGCTGATAAGCTCCGAGGTGAGATGGCTCTCAGAAAAGCTCTCTTACATCGCCGAAGAGCTTGGCC
TGAACTTCAGGCCTTTTGAAGGAAACTCTTACGATCGGAACTTTGTTCACTTTGAGGGGAACGAGAACAGGAAGATAGTC
TTTTTCCATCTGTTTATGCCAACGGGTGAAGTCGTGAAGATTGAGGTTAACTTTTTTGAACCGGTGCTGTTTGAGGAGAA
GAAAGTACTGGCTAAGACGCTTCTTGATGGAGTTAAGTTAGAAGATGAAGAGAAGACATACTTCTTCGAGGAGCTTGAAC
GGTACTTAACGCTTTCCGTGACGGCGTATTCTCCTGAGGAAATTCTGGCCGAAAAGATTAGGGCCATTTTAACCCGCAGG
ATTCAAAAGCTGAGGGATTTCTACGACGTTTTCATGCTCCACAAAGCGGGTTATGATTACTCGAACGTTATTGATGAAGC
CCTTTAG

Antitoxin


Download         Length: 154 a.a.        Molecular weight: 17870.08 Da        Isoelectric Point: 10.1604

>AT20113 WP_010868683.1 NC_000868:1523693-1524154 [Pyrococcus abyssi GE5]
VKTLEEYKFGKTPDPMTLIAKAMNKLKLKWYFGLYTALRLNGATYEYYSRIFLVTPVITRPKPITILGESVQFIKLKESL
LGFGVIKRGEIQYSDLEKTLLDFIYLKRYNKRLNADAVVREYITKIEKEKLVEYSKAYPKSVQREVEVIVSRG

Download         Length: 462 bp

>AT20113 NC_000868:1523693-1524154 [Pyrococcus abyssi GE5]
GTGAAAACTCTCGAGGAATACAAGTTCGGAAAGACTCCAGATCCAATGACTTTAATTGCAAAGGCCATGAACAAGTTAAA
GCTGAAGTGGTACTTCGGCCTGTACACGGCTTTAAGACTAAACGGGGCAACATATGAATACTACTCCCGAATTTTTCTGG
TAACTCCGGTGATAACAAGACCAAAACCGATTACAATTCTCGGCGAGAGTGTTCAGTTCATCAAGCTAAAAGAATCTCTC
CTGGGCTTTGGAGTGATTAAACGAGGAGAAATCCAGTATTCAGACTTAGAAAAAACCCTGCTGGACTTTATTTATCTAAA
ACGGTACAACAAACGCCTTAATGCAGATGCCGTTGTACGGGAATACATTACAAAGATAGAAAAAGAAAAGCTAGTAGAAT
ACTCTAAAGCATACCCAAAATCAGTTCAGAGGGAGGTTGAGGTCATTGTTTCCAGGGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References