Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2558262..2558533 Replicon chromosome
Accession NZ_CP074019
Organism Escherichia coli strain PM22

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2558300..2558403 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2558262..2558533 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFU87_RS12165 2555419..2556858 + 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KFU87_RS12170 2556976..2557212 + 237 WP_001295499.1 YebV family protein -
KFU87_RS12175 2557317..2557508 + 192 WP_001296140.1 YebW family protein -
KFU87_RS12180 2557509..2558165 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2558262..2558533 + 272 - - Antitoxin
- 2558300..2558403 - 104 - - Toxin
KFU87_RS12185 2558561..2558902 - 342 WP_000976472.1 YebY family protein -
KFU87_RS12190 2558915..2559787 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
KFU87_RS12195 2559791..2560165 - 375 WP_000204700.1 CopC domain-containing protein YobA -
KFU87_RS12200 2560304..2560534 + 231 WP_000916763.1 DNA polymerase III subunit theta -
KFU87_RS12205 2560636..2561292 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
KFU87_RS12210 2561316..2561978 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T201110 NZ_CP074019:c2558403-2558300 [Escherichia coli]
GGCAAGGCAACTAAGCCTGTATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT201110 NZ_CP074019:2558262-2558533 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATACAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References