Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2047319..2047590 Replicon chromosome
Accession NZ_CP074012
Organism Escherichia coli strain PI24

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2047449..2047552 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2047319..2047590 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFU81_RS10010 2043874..2044536 - 663 WP_219371335.1 exodeoxyribonuclease X -
KFU81_RS10015 2044560..2045216 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
KFU81_RS10020 2045318..2045548 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KFU81_RS10025 2045687..2046061 + 375 WP_000168747.1 CopC domain-containing protein YobA -
KFU81_RS10030 2046065..2046937 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
KFU81_RS10035 2046950..2047291 + 342 WP_000976476.1 YebY family protein -
- 2047319..2047590 - 272 - - Antitoxin
- 2047449..2047552 + 104 - - Toxin
KFU81_RS10040 2047687..2048343 + 657 WP_053885983.1 protein-serine/threonine phosphatase -
KFU81_RS10045 2048344..2048535 - 192 WP_001296140.1 YebW family protein -
KFU81_RS10050 2048640..2048876 - 237 WP_001295499.1 YebV family protein -
KFU81_RS10055 2048994..2050433 - 1440 WP_024174420.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T201083 NZ_CP074012:2047449-2047552 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT201083 NZ_CP074012:c2047590-2047319 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References