Detailed information of TA system TA020106

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 5079627..5080143
• Replicon: chromosome
• Accession: LT629788
• Organism: Pseudomonas moraviensis strain BS3668

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SAMN04490196_4763
• Protein ID: SDU71898.1
• Coordinates: 5079862..5080143 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: SAMN04490196_4762
• Protein ID: SDU71892.1
• Coordinates: 5079627..5079872 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAMN04490196_4758	5075072..5076610	+	1539	SDU71869.1	Major Facilitator Superfamily protein	-
SAMN04490196_4759	5076639..5077706	+	1068	SDU71875.1	membrane fusion protein, multidrug efflux system	-
SAMN04490196_4760	5077703..5079271	+	1569	SDU71881.1	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family	-
SAMN04490196_4761	5079350..5079589	+	240	SDU71886.1	Protein of unknown function	-
SAMN04490196_4762	5079627..5079872	+	246	SDU71892.1	antitoxin StbD	Antitoxin
SAMN04490196_4763	5079862..5080143	+	282	SDU71898.1	mRNA interferase RelE/StbE	Toxin
SAMN04490196_4764	5080480..5080935	+	456	SDU71905.1	transcriptional regulator, MarR family	-
SAMN04490196_4765	5080932..5082995	+	2064	SDU71911.1	Uncharacterized membrane protein YccC	-
SAMN04490196_4766	5082992..5083201	+	210	SDU71918.1	Protein of unknown function	-
SAMN04490196_4767	5083198..5084085	+	888	SDU71924.1	RND family efflux transporter, MFP subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-70)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10814.71 Da
• Isoelectric Point: 10.5399

>T20106 SDU71898.1 LT629788:5079862-5080143 [Pseudomonas moraviensis]
MTYKLEFLPSAHKEWNKLGHTLREQFKKKLGERLKLPRIPADALHSMPDCYKIKLKASGYRLVYQVIDERVVVSVLAVGK
RERSSVYDAAKNR

Nucleotide

• Length: 282 bp

>T20106 LT629788:5079862-5080143 [Pseudomonas moraviensis]
ATGACTTATAAGCTTGAGTTTCTGCCGTCTGCGCACAAAGAGTGGAACAAGCTGGGTCATACGTTGCGGGAGCAGTTCAA
AAAGAAGCTGGGTGAGAGGCTGAAGCTTCCCAGAATCCCGGCTGACGCCCTCCACAGCATGCCCGACTGCTACAAAATCA
AACTCAAAGCCTCGGGATATCGATTGGTTTACCAAGTCATCGACGAACGAGTCGTGGTTTCCGTGCTAGCGGTTGGCAAG
CGCGAACGCAGCAGCGTTTACGATGCTGCCAAGAACCGTTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8806.13 Da
• Isoelectric Point: 4.4988

>AT20106 SDU71892.1 LT629788:5079627-5079872 [Pseudomonas moraviensis]
MQSVLADMAVSVSELKKNPTAVLNGAHGGAVAVLNHNRVMGYMVPAEVYEAMMERLDDLELADIVRSRLHETPISVSLDD
L

Nucleotide

• Length: 246 bp

>AT20106 LT629788:5079627-5079872 [Pseudomonas moraviensis]
ATGCAAAGTGTTCTTGCCGATATGGCTGTCAGTGTCTCTGAACTAAAGAAAAATCCTACTGCCGTGTTGAACGGTGCACA
TGGGGGGGCCGTCGCTGTCCTCAACCACAATCGCGTCATGGGTTATATGGTGCCGGCCGAAGTTTACGAAGCGATGATGG
AGCGGCTTGATGATCTTGAGCTGGCTGACATCGTTCGTTCGCGCCTTCACGAAACGCCCATTTCGGTAAGCCTGGATGAC
TTATAA