Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2043589..2043860 Replicon chromosome
Accession NZ_CP074005
Organism Escherichia coli strain PI12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2043719..2043822 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2043589..2043860 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFU69_RS09735 2040144..2040806 - 663 WP_000944256.1 exodeoxyribonuclease X -
KFU69_RS09740 2040830..2041486 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
KFU69_RS09745 2041588..2041818 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KFU69_RS09750 2041957..2042331 + 375 WP_000168747.1 CopC domain-containing protein YobA -
KFU69_RS09755 2042335..2043207 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
KFU69_RS09760 2043220..2043561 + 342 WP_000976472.1 YebY family protein -
- 2043589..2043860 - 272 - - Antitoxin
- 2043719..2043822 + 104 - - Toxin
KFU69_RS09765 2043957..2044613 + 657 WP_000812733.1 protein-serine/threonine phosphatase -
KFU69_RS09770 2044614..2044805 - 192 WP_001338167.1 YebW family protein -
KFU69_RS09775 2044910..2045146 - 237 WP_001338166.1 YebV family protein -
KFU69_RS09780 2045264..2046703 - 1440 WP_024238487.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2005574..2044613 39039


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T201037 NZ_CP074005:2043719-2043822 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT201037 NZ_CP074005:c2043860-2043589 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References