Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 47198..47733 Replicon plasmid pYLMB10a
Accession NZ_CP073989
Organism Escherichia coli strain MB10

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KFU65_RS22345 Protein ID WP_032206513.1
Coordinates 47198..47485 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KFU65_RS22350 Protein ID WP_032206515.1
Coordinates 47482..47733 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFU65_RS22335 (KFU65_22145) 42479..45976 + 3498 WP_001038839.1 autotransporter outer membrane beta-barrel domain-containing protein -
KFU65_RS22340 (KFU65_22150) 46141..46838 + 698 WP_225393497.1 IS1 family transposase -
KFU65_RS22345 (KFU65_22155) 47198..47485 - 288 WP_032206513.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KFU65_RS22350 (KFU65_22160) 47482..47733 - 252 WP_032206515.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KFU65_RS22355 (KFU65_22165) 48317..52285 + 3969 Protein_52 helicase-related protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..134191 134191


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11130.20 Da        Isoelectric Point: 10.5833

>T200956 WP_032206513.1 NZ_CP073989:c47485-47198 [Escherichia coli]
MTYTVKFRDDALKEWLRLDKTIQQQFAKKLKKCSENPHIASAKLRGLKDCYKIKLRASGFRLVYQIIDDMLIIAVVAVGK
RERSNVYHLASERMK

Download         Length: 288 bp

>T200956 NZ_CP098201:c4901818-4901711 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CATGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9161.35 Da        Isoelectric Point: 4.0927

>AT200956 WP_032206515.1 NZ_CP073989:c47733-47482 [Escherichia coli]
MPSIILSDTSASVSELKKNPMATVSAGEGYPVAILNRNQPAFYCVPAELYERMLDALDDQELVKLVTERSSQSLHDVDLD
SYL

Download         Length: 252 bp

>AT200956 NZ_CP098201:4901866-4901932 [Escherichia coli]
GGTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References