Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1952149..1952420 Replicon chromosome
Accession NZ_CP073949
Organism Escherichia coli strain MB50

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1952279..1952382 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1952149..1952420 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFU75_RS09455 1948704..1949366 - 663 WP_000944258.1 exodeoxyribonuclease X -
KFU75_RS09460 1949390..1950046 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
KFU75_RS09465 1950148..1950378 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KFU75_RS09470 1950517..1950891 + 375 WP_000168747.1 CopC domain-containing protein YobA -
KFU75_RS09475 1950895..1951767 + 873 WP_257187389.1 copper homeostasis membrane protein CopD -
KFU75_RS09480 1951780..1952121 + 342 WP_072651707.1 YebY family protein -
- 1952149..1952420 - 272 - - Antitoxin
- 1952279..1952382 + 104 - - Toxin
KFU75_RS09485 1952517..1953173 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
KFU75_RS09490 1953174..1953365 - 192 WP_001338167.1 YebW family protein -
KFU75_RS09495 1953470..1953706 - 237 WP_001338166.1 YebV family protein -
KFU75_RS09500 1953824..1955263 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T200752 NZ_CP073949:1952279-1952382 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT200752 NZ_CP073949:c1952420-1952149 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References