Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1527287..1528056 Replicon chromosome
Accession NZ_CP073910
Organism Sphingobium phenoxybenzoativorans strain Tas13

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag KFK14_RS07355 Protein ID WP_212610421.1
Coordinates 1527529..1528056 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag KFK14_RS07350 Protein ID WP_021244025.1
Coordinates 1527287..1527532 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFK14_RS07330 (KFK14_07330) 1522440..1522946 + 507 WP_212610417.1 hypothetical protein -
KFK14_RS07335 (KFK14_07335) 1522994..1524037 + 1044 WP_212610418.1 TIGR03857 family LLM class F420-dependent oxidoreductase -
KFK14_RS24195 1524149..1524280 - 132 WP_281417178.1 hypothetical protein -
KFK14_RS07340 (KFK14_07340) 1524580..1525827 + 1248 WP_212610419.1 acyl-CoA dehydrogenase family protein -
KFK14_RS07345 (KFK14_07345) 1526229..1527005 + 777 WP_212610420.1 LuxR family transcriptional regulator -
KFK14_RS07350 (KFK14_07350) 1527287..1527532 + 246 WP_021244025.1 DUF1778 domain-containing protein Antitoxin
KFK14_RS07355 (KFK14_07355) 1527529..1528056 + 528 WP_212610421.1 GNAT family N-acetyltransferase Toxin
KFK14_RS07360 (KFK14_07360) 1528300..1528755 + 456 WP_212610422.1 hypothetical protein -
KFK14_RS07365 (KFK14_07365) 1528742..1532512 - 3771 WP_212610423.1 conjugal transfer protein TraG N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(2-77)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19080.69 Da        Isoelectric Point: 7.0401

>T200525 WP_212610421.1 NZ_CP073910:1527529-1528056 [Sphingobium phenoxybenzoativorans]
MTLPSWHEEAISKAHDRASFDCGDNDLNVYLQRYARQSHEAGGAKTFLAIDDTDNKTVLGFYSIAPGSMDHADTPELTRR
GLARHEVPGFRLARLATDVRVQGKGLGGQLLGAIGRRCIRVAAEIGGVILIIDAKNERAADWYASCGAIPLHDKPLTLIL
PFATLERELRAAGQF

Download         Length: 528 bp

>T200525 NZ_CP097884:2404759-2405013 [Escherichia coli str. K-12 substr. MG1655]
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8930.43 Da        Isoelectric Point: 10.1783

>AT200525 WP_021244025.1 NZ_CP073910:1527287-1527532 [Sphingobium phenoxybenzoativorans]
MSLRIRPEQKALLARAAALKHTDLTTFVTRSALREAENVIEEAERTKLSERDSLLVLDLLENPPPANAKLRAAIAAMPKL
A

Download         Length: 246 bp

>AT200525 NZ_CP097884:2404511-2404762 [Escherichia coli str. K-12 substr. MG1655]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References