200340

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4740804..4741154 Replicon chromosome
Accession NZ_CP073820
Organism Xanthomonas oryzae strain PXO99A-gx

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag KFK26_RS22035 Protein ID WP_011257368.1
Coordinates 4740804..4740938 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag KFK26_RS22040 Protein ID WP_011407410.1
Coordinates 4741002..4741154 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFK26_RS22020 (KFK26_22075) 4737818..4738762 - 945 WP_027704118.1 MBL fold metallo-hydrolase -
KFK26_RS22025 (KFK26_22080) 4738893..4740182 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
KFK26_RS22030 (KFK26_22085) 4740351..4740560 - 210 WP_011407411.1 CsbD family protein -
KFK26_RS22035 (KFK26_22090) 4740804..4740938 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
KFK26_RS22040 (KFK26_22095) 4741002..4741154 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
KFK26_RS22045 (KFK26_22100) 4741262..4742185 - 924 WP_011407409.1 arginase -
KFK26_RS22050 4742507..4742725 + 219 Protein_4227 hypothetical protein -
KFK26_RS22055 (KFK26_22105) 4742717..4743181 + 465 Protein_4228 hypothetical protein -
KFK26_RS22060 4743178..4743720 + 543 Protein_4229 GTPase -
KFK26_RS22065 (KFK26_22120) 4744200..4744883 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T200340 WP_011257368.1 NZ_CP073820:c4740938-4740804 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T200340 NZ_CP097831:4357384-4357602 [Shigella flexneri]
ATGTCCGAAAAACCTTTAACAAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT200340 WP_011407410.1 NZ_CP073820:c4741154-4741002 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT200340 NZ_CP097831:4356984-4357358 [Shigella flexneri]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAATCATGGTTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGCAGTTATGGTATTAATATGCAGGCTCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAACGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References