Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3276320..3277839 Replicon chromosome
Accession NZ_CP073820
Organism Xanthomonas oryzae strain PXO99A-gx

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag KFK26_RS15035 Protein ID WP_011259680.1
Coordinates 3276320..3277243 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A0K0GMG7
Locus tag KFK26_RS15040 Protein ID WP_012445456.1
Coordinates 3277240..3277839 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFK26_RS15000 (KFK26_15055) 3271476..3271745 + 270 WP_153296781.1 hypothetical protein -
KFK26_RS15005 (KFK26_15060) 3271919..3272071 + 153 Protein_2895 SAM-dependent methyltransferase -
KFK26_RS15010 (KFK26_15065) 3272183..3273559 + 1377 Protein_2896 IS5 family transposase -
KFK26_RS15015 (KFK26_15070) 3273579..3274111 + 533 Protein_2897 methyltransferase domain-containing protein -
KFK26_RS15020 (KFK26_15075) 3274128..3274637 - 510 WP_011259678.1 hypothetical protein -
KFK26_RS15025 (KFK26_15080) 3275062..3275304 - 243 WP_011259679.1 hypothetical protein -
KFK26_RS15030 3275770..3276240 + 471 WP_228329666.1 helix-turn-helix domain-containing protein -
KFK26_RS15035 (KFK26_15095) 3276320..3277243 - 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
KFK26_RS15040 (KFK26_15100) 3277240..3277839 - 600 WP_012445456.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
KFK26_RS15045 (KFK26_15105) 3278204..3278494 + 291 WP_229002604.1 FaeA/PapI family transcriptional regulator -
KFK26_RS15050 (KFK26_15110) 3278526..3279014 + 489 WP_027703988.1 BrxE family protein -
KFK26_RS15055 (KFK26_15115) 3279528..3279529 - 2 WP_094187763.1 IS5 family transposase -
KFK26_RS15060 (KFK26_15120) 3279935..3280968 - 1034 Protein_2906 IS630 family transposase -
KFK26_RS15070 3281467..3281757 + 291 WP_011409031.1 hypothetical protein -
KFK26_RS15075 3281738..3282112 + 375 WP_229002607.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T200339 WP_011259680.1 NZ_CP073820:c3277243-3276320 [Xanthomonas oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T200339 NZ_CP097831:4054730-4054960 [Shigella flexneri]
ATGAAGGTATACGGCAGCAATCTCGGAGAACCTCACACCAGCGCCTTTGGTGACGGGCTTTTCGAACTCAGAATTAAAGG
CAACGATGGGATCGCGCGTGTTTTTTACTGCACTCTGACAGGGAAACGCATCATCATGCTGCATAGTTTTGTAAAGAAAG
CGCAGAAAACACCGCCAGCCGAACGCAAGAAAGCTGAAACCAGAATGAAGGAGGTTAAGCATGACTGGTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22051.76 Da        Isoelectric Point: 10.1240

>AT200339 WP_012445456.1 NZ_CP073820:c3277839-3277240 [Xanthomonas oryzae]
MDTTIDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT200339 NZ_CP097831:4054950-4055258 [Shigella flexneri]
ATGACTGGTAAACGCACTCTCCCCACCATGACACACGACGAAATGGCAGCCAAATGGATGGAAGACCCGGCTTTTAAAGC
AGAATACGACGCTATCGCTGACGAATTCGCACTGCTTGATGAAATGCTGGCAGCACGCAAAGAAGCTGGCTTAACTCAGG
CTGAAGTTGCCGAGCGAATGGGAACAAAAGCGACCGCGATCACCAGAATGGAAAGTAATCTCGCATCAGGTATCAGCGGC
CCATCATTTGCCACACTAAAAAAATTCGCCCGCGCTACTGGAAAAAAACTCCAGATCCGCTTCGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A0K0GMG7

References