Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relB-parE/ParE-RHH |
Location | 1973205..1973761 | Replicon | chromosome |
Accession | NZ_CP073820 | ||
Organism | Xanthomonas oryzae strain PXO99A-gx |
Toxin (Protein)
Gene name | parE | Uniprot ID | - |
Locus tag | KFK26_RS09160 | Protein ID | WP_229002778.1 |
Coordinates | 1973510..1973761 (+) | Length | 84 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A854CIX2 |
Locus tag | KFK26_RS09155 | Protein ID | WP_011408759.1 |
Coordinates | 1973205..1973483 (+) | Length | 93 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KFK26_RS09135 (KFK26_09140) | 1968322..1968879 | - | 558 | WP_011259349.1 | DNA-3-methyladenine glycosylase | - |
KFK26_RS09140 (KFK26_09145) | 1969029..1969994 | - | 966 | WP_109181928.1 | IS1595-like element ISXo5 family transposase | - |
KFK26_RS09145 (KFK26_09150) | 1970575..1971759 | + | 1185 | WP_011408397.1 | IS256-like element IS1113 family transposase | - |
KFK26_RS09150 (KFK26_09160) | 1972665..1973009 | + | 345 | WP_198912817.1 | hypothetical protein | - |
KFK26_RS09155 (KFK26_09170) | 1973205..1973483 | + | 279 | WP_011408759.1 | CopG family ribbon-helix-helix protein | Antitoxin |
KFK26_RS09160 (KFK26_09175) | 1973510..1973761 | + | 252 | WP_229002778.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
KFK26_RS09165 (KFK26_09180) | 1973838..1974092 | + | 255 | WP_198912806.1 | hypothetical protein | - |
KFK26_RS23460 | 1974085..1974219 | + | 135 | WP_011051575.1 | hypothetical protein | - |
KFK26_RS09170 (KFK26_09185) | 1974288..1974542 | + | 255 | WP_223293127.1 | hypothetical protein | - |
KFK26_RS09175 | 1974759..1974878 | + | 120 | Protein_1776 | IS3 family transposase | - |
KFK26_RS23465 | 1974847..1974975 | + | 129 | WP_012444694.1 | hypothetical protein | - |
KFK26_RS09180 (KFK26_09190) | 1975044..1975842 | + | 799 | WP_094187731.1 | IS5 family transposase | - |
KFK26_RS09190 (KFK26_09200) | 1976258..1976659 | - | 402 | WP_011259345.1 | H-NS family nucleoid-associated regulatory protein | - |
KFK26_RS09195 (KFK26_09205) | 1976881..1977057 | + | 177 | Protein_1780 | DUF3606 domain-containing protein | - |
KFK26_RS09200 (KFK26_09215) | 1977339..1977655 | + | 317 | Protein_1781 | ATP-dependent DNA ligase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | IScluster/Tn | - | - | 1969029..1975842 | 6813 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 84 a.a. Molecular weight: 9617.95 Da Isoelectric Point: 9.9718
>T200338 WP_229002778.1 NZ_CP073820:1973510-1973761 [Xanthomonas oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILALRHQKE
AGY
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILALRHQKE
AGY
Download Length: 252 bp
>T200338 NZ_CP097831:3516639-3516746 [Shigella flexneri]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTGCCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTGCCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 93 a.a. Molecular weight: 10826.11 Da Isoelectric Point: 4.9736
>AT200338 WP_011408759.1 NZ_CP073820:1973205-1973483 [Xanthomonas oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK
Download Length: 279 bp
>AT200338 NZ_CP097831:c3516583-3516527 [Shigella flexneri]
TCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTC
TCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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