Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 2312330..2312844 Replicon chromosome
Accession NZ_CP073797
Organism Dactylosporangium matsuzakiense strain NRRL B-16293

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag Dmats_RS10185 Protein ID WP_223102274.1
Coordinates 2312330..2312590 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag Dmats_RS10190 Protein ID WP_246656137.1
Coordinates 2312587..2312844 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Dmats_RS10165 (Dmats_10125) 2307561..2308556 + 996 WP_223102270.1 ferrochelatase -
Dmats_RS10170 (Dmats_10130) 2308580..2309368 + 789 WP_223102271.1 HAD-IIA family hydrolase -
Dmats_RS10175 (Dmats_10135) 2310646..2311449 - 804 WP_261963546.1 DUF3097 domain-containing protein -
Dmats_RS10180 (Dmats_10140) 2311525..2312307 + 783 WP_223102273.1 hypothetical protein -
Dmats_RS10185 (Dmats_10145) 2312330..2312590 - 261 WP_223102274.1 Txe/YoeB family addiction module toxin Toxin
Dmats_RS10190 (Dmats_10150) 2312587..2312844 - 258 WP_246656137.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
Dmats_RS10195 (Dmats_10155) 2312980..2314296 - 1317 WP_261966005.1 serine hydrolase domain-containing protein -
Dmats_RS10200 (Dmats_10160) 2314391..2314825 + 435 WP_246656138.1 NfeD family protein -
Dmats_RS10205 (Dmats_10165) 2314904..2315953 + 1050 WP_261966006.1 SPFH domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(5-70)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10173.56 Da        Isoelectric Point: 8.0751

>T200312 WP_223102274.1 NZ_CP073797:c2312590-2312330 [Dactylosporangium matsuzakiense]
VKIRFTDEGWHDYLYWQGQDRRTLRRINALIADLQRDPDGPGIGKPELLRSHLSGLRSRRIDETHRLVYTVEAGEIIILA
CRFHYE

Download         Length: 261 bp

>T200312 NZ_CP097828:c1716349-1716242 [Shigella flexneri]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9493.58 Da        Isoelectric Point: 4.8134

>AT200312 WP_246656137.1 NZ_CP073797:c2312844-2312587 [Dactylosporangium matsuzakiense]
VTGAISASEARRSLFPLIERVNQDHTPIEIVSRHGNAVLVSKDDWDAIVETDYLLRTPANARHLAESIDTWRAGKATVRE
LDLDE

Download         Length: 258 bp

>AT200312 NZ_CP097828:1716406-1716461 [Shigella flexneri]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References