Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VapB |
| Location | 2189595..2190226 | Replicon | chromosome |
| Accession | NZ_CP073797 | ||
| Organism | Dactylosporangium matsuzakiense strain NRRL B-16293 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | Dmats_RS09620 | Protein ID | WP_261963473.1 |
| Coordinates | 2189595..2190020 (-) | Length | 142 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | Dmats_RS09625 | Protein ID | WP_261963474.1 |
| Coordinates | 2190017..2190226 (-) | Length | 70 a.a. |
Genomic Context
Location: 2185901..2187361 (1461 bp)
Type: Others
Protein ID: WP_223102175.1
Type: Others
Protein ID: WP_223102175.1
Location: 2192086..2193120 (1035 bp)
Type: Others
Protein ID: WP_261963478.1
Type: Others
Protein ID: WP_261963478.1
Location: 2187464..2188171 (708 bp)
Type: Others
Protein ID: WP_261963471.1
Type: Others
Protein ID: WP_261963471.1
Location: 2188182..2189537 (1356 bp)
Type: Others
Protein ID: WP_261963472.1
Type: Others
Protein ID: WP_261963472.1
Location: 2189595..2190020 (426 bp)
Type: Toxin
Protein ID: WP_261963473.1
Type: Toxin
Protein ID: WP_261963473.1
Location: 2190017..2190226 (210 bp)
Type: Antitoxin
Protein ID: WP_261963474.1
Type: Antitoxin
Protein ID: WP_261963474.1
Location: 2190288..2190884 (597 bp)
Type: Others
Protein ID: WP_261963475.1
Type: Others
Protein ID: WP_261963475.1
Location: 2190881..2191549 (669 bp)
Type: Others
Protein ID: WP_261963476.1
Type: Others
Protein ID: WP_261963476.1
Location: 2191559..2191993 (435 bp)
Type: Others
Protein ID: WP_261963477.1
Type: Others
Protein ID: WP_261963477.1
Loading, please wait
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| Dmats_RS09605 (Dmats_09560) | 2185901..2187361 | + | 1461 | WP_223102175.1 | argininosuccinate synthase | - |
| Dmats_RS09610 (Dmats_09565) | 2187464..2188171 | - | 708 | WP_261963471.1 | uracil-DNA glycosylase | - |
| Dmats_RS09615 (Dmats_09570) | 2188182..2189537 | - | 1356 | WP_261963472.1 | MFS transporter | - |
| Dmats_RS09620 (Dmats_09575) | 2189595..2190020 | - | 426 | WP_261963473.1 | PIN domain nuclease | Toxin |
| Dmats_RS09625 (Dmats_09580) | 2190017..2190226 | - | 210 | WP_261963474.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
| Dmats_RS09630 (Dmats_09585) | 2190288..2190884 | - | 597 | WP_261963475.1 | MBL fold metallo-hydrolase | - |
| Dmats_RS09635 (Dmats_09590) | 2190881..2191549 | - | 669 | WP_261963476.1 | maleylpyruvate isomerase family mycothiol-dependent enzyme | - |
| Dmats_RS09640 (Dmats_09595) | 2191559..2191993 | - | 435 | WP_261963477.1 | hypothetical protein | - |
| Dmats_RS09645 (Dmats_09600) | 2192086..2193120 | + | 1035 | WP_261963478.1 | ribosome small subunit-dependent GTPase A | - |
Associated MGEs
Loading, please wait
MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 142 a.a. Molecular weight: 15500.81 Da Isoelectric Point: 5.5353
>T200311 WP_261963473.1 NZ_CP073797:c2190020-2189595 [Dactylosporangium matsuzakiense]
MTPVRFLVDTSALVRLLRNHQLRVRWEPQITAGVIGICPITELELLHSARSKTDREEWLELLNATFAWVPMPEQIFVRAT
EVQAAMTASGTHRSAGAVDLLLAATAELSGLTLVHYDHDFDEIVKTTGQAAVWLAPAGSIS
MTPVRFLVDTSALVRLLRNHQLRVRWEPQITAGVIGICPITELELLHSARSKTDREEWLELLNATFAWVPMPEQIFVRAT
EVQAAMTASGTHRSAGAVDLLLAATAELSGLTLVHYDHDFDEIVKTTGQAAVWLAPAGSIS
Download Length: 426 bp
>T200311 NZ_CP097828:c1636577-1636302 [Shigella flexneri]
ATGAGAACCAAGGTACAGGCTTTACGGAAGAAACAAAAAAATACATTGGATCAAATATTTAAAACTCCTGTTCCTCAAGG
GATCAAGTGGTCTGATATAGAGTCACTGGTTAAAGCATTAGGCGGAGAAATTAAGAAAGGAAGAGGTTCGCGTTGCAAGT
TCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGTCGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTG
TGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA
ATGAGAACCAAGGTACAGGCTTTACGGAAGAAACAAAAAAATACATTGGATCAAATATTTAAAACTCCTGTTCCTCAAGG
GATCAAGTGGTCTGATATAGAGTCACTGGTTAAAGCATTAGGCGGAGAAATTAAGAAAGGAAGAGGTTCGCGTTGCAAGT
TCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGTCGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTG
TGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA
Antitoxin
Download Length: 70 a.a. Molecular weight: 7408.41 Da Isoelectric Point: 5.0323
>AT200311 WP_261963474.1 NZ_CP073797:c2190226-2190017 [Dactylosporangium matsuzakiense]
MTKVLIDIDDDALAEASALLGTKTKKDTVNTALRSTADQLRRAKALTRLAELGEAGAFDELLDKSAYRG
MTKVLIDIDDDALAEASALLGTKTKKDTVNTALRSTADQLRRAKALTRLAELGEAGAFDELLDKSAYRG
Download Length: 210 bp
>AT200311 NZ_CP097828:c1636305-1635946 [Shigella flexneri]
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCAGCTGTTATTACCTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGTATTCAGGGGCTGCAAAAAGAAGGAG
AGCTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCAGCTGTTATTACCTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGTATTCAGGGGCTGCAAAAAGAAGGAG
AGCTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA