Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 11257152..11257630 Replicon chromosome
Accession NZ_CP073767
Organism Dactylosporangium aurantiacum strain NRRL B-8018

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag Daura_RS50510 Protein ID WP_033367965.1
Coordinates 11257152..11257406 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag Daura_RS50515 Protein ID WP_245635824.1
Coordinates 11257403..11257630 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Daura_RS50495 (Daura_50225) 11253382..11254062 + 681 WP_052387611.1 YdcF family protein -
Daura_RS50500 (Daura_50230) 11254085..11256058 - 1974 WP_162189863.1 caspase family protein -
Daura_RS50505 (Daura_50235) 11256039..11256386 - 348 WP_156089925.1 hypothetical protein -
Daura_RS50510 (Daura_50240) 11257152..11257406 - 255 WP_033367965.1 Txe/YoeB family addiction module toxin Toxin
Daura_RS50515 (Daura_50245) 11257403..11257630 - 228 WP_245635824.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
Daura_RS50520 (Daura_50250) 11258249..11259037 - 789 WP_081970929.1 cellulose-binding domain-containing protein -
Daura_RS50525 (Daura_50255) 11259181..11260284 - 1104 WP_052387018.1 glycoside hydrolase family 19 protein -
Daura_RS50530 (Daura_50260) 11261062..11262054 + 993 WP_052387019.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 11243377..11275130 31753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-59)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10218.41 Da        Isoelectric Point: 8.9594

>T200176 WP_033367965.1 NZ_CP073767:c11257406-11257152 [Dactylosporangium aurantiacum]
VKVQFASRGWDDYLSWQQDRQMLRRVNALIEDIRRNGHEGIGKPEQLRGNWSGFWSRRIDQEHRLVYRIADDTVQIAQCR
YHYE

Download         Length: 255 bp

>T200176 NZ_CP097719:c3704351-3704049 [Escherichia coli]
ATGGCTCAAAAGAAAAATATAAGGAGTTTTCGTGATGCCTGGTTGGCTGATTTTTTTGTCCATTCAACGCCACATCGAAA
GATCCCTGCTGAAATCCATACCACGTTATCACGAAAGTTGGACATCATTAATGCTGCCACTTCTCATCGGGATTTACGCT
CCCCTCCGGGGAACCGATACGAAGAGTTATCCGGGAAATTACAGGAATACTCCTCCATTAGAGTGAATAAACAGTACCGA
CTGATTTTTAAATGGGTTAATGGCAAGGCCGAAGAATTGTTTTTAGACCCACACAACTACTAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8121.95 Da        Isoelectric Point: 4.1048

>AT200176 WP_245635824.1 NZ_CP073767:c11257630-11257403 [Dactylosporangium aurantiacum]
MLDHVVDDAEEVVITRSGHESAVIISLREYESLKETAYLMASPANARRLNEAIEELRAGGGEVHDLLDADEASAA

Download         Length: 228 bp

>AT200176 NZ_CP097719:c3704013-3703672 [Escherichia coli]
ATGAAACAGGCAACAAGAAAACCGACGACACCCGGAGATATTCTTCTCTATGAATATCTGGAACCGCTCGATTTGAAAAT
CAATGAGTTAGCAGAGTTGCTGCATGTTCATCGTAATAGCGTCAGTGCACTGATCAATAACAATCGTAAACTCACCACTG
AGATGGCATTCCGTCTGGCGAAAGTTTTTGATACCACAGTCGATTTTTGGCTAAACCTCCAGGCGGCAGTTGATCTTTGG
GAAGTTGAAAACAACATGCGTACCCAGGAAGAATTGGGACGGATTGAAACAGTGGCTGAATATTTGGCACGCCGTGAAGA
GCGTGCAAAAAAGGTCGCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References