Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 964366..964896 Replicon chromosome
Accession NZ_CP073745
Organism Bacterioplanoides sp. SCSIO 12839

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KFF03_RS04495 Protein ID WP_255859171.1
Coordinates 964642..964896 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag KFF03_RS04490 Protein ID WP_255859170.1
Coordinates 964366..964620 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFF03_RS04465 (KFF03_04445) 960729..961313 + 585 WP_255859162.1 aminodeoxychorismate/anthranilate synthase component II -
KFF03_RS04470 (KFF03_04450) 961328..962374 + 1047 WP_255859164.1 anthranilate phosphoribosyltransferase -
KFF03_RS04475 (KFF03_04455) 962389..963189 + 801 WP_255859165.1 indole-3-glycerol phosphate synthase TrpC -
KFF03_RS04480 (KFF03_04460) 963349..963711 + 363 WP_255859167.1 hypothetical protein -
KFF03_RS04485 (KFF03_04465) 963728..964153 - 426 WP_255859168.1 BLUF domain-containing protein -
KFF03_RS04490 (KFF03_04470) 964366..964620 + 255 WP_255859170.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KFF03_RS04495 (KFF03_04475) 964642..964896 + 255 WP_255859171.1 Txe/YoeB family addiction module toxin Toxin
KFF03_RS04500 (KFF03_04480) 965310..966242 + 933 WP_255859173.1 retron St85 family RNA-directed DNA polymerase -
KFF03_RS04505 (KFF03_04485) 966235..967827 + 1593 WP_255859174.1 retron Ec78 anti-phage system effector ATPase PtuA -
KFF03_RS04510 (KFF03_04490) 967853..968512 + 660 WP_255859175.1 retron Ec78 anti-phage system effector HNH endonuclease PtuB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10072.74 Da        Isoelectric Point: 10.1736

>T200145 WP_255859171.1 NZ_CP073745:964642-964896 [Bacterioplanoides sp. SCSIO 12839]
MKLIFSSKAWESYLYWQSTDKKMLKRINALIKEIQRTPFEGTGKPEPLKHGLMGYWSRRINDEHRLVYKVEDGAVLIAQL
RYHY

Download         Length: 255 bp

>T200145 NZ_CP097716:c3919879-3919502 [Escherichia coli]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGATACTGCTGTC
CCGACTGCTGGACCAGCACTACGGCCTCACACTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTTGTTGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGAATTC
AGTGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCCGGGCGACTGGCCTGATGACCCGCGA
CAATTACCGAACGGTAAATAACATTACCCTGGGTAAGTATCAGGAGGCGAAACGATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9373.60 Da        Isoelectric Point: 4.1948

>AT200145 WP_255859170.1 NZ_CP073745:964366-964620 [Bacterioplanoides sp. SCSIO 12839]
MDAISYTAARANLAKTMEQVCNDHAPVIITRKSEEPVVMMSLEDYQAMQETTYLLRSPANARNLLESIAELESGQSAERV
LLED

Download         Length: 255 bp

>AT200145 NZ_CP097716:c3920336-3919968 [Escherichia coli]
GTGTCAGACACACTCCCCGGGACAATACTTCCCGACGACAATCACGACCGCCTCTGGTGGGGACTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGAAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGATGCAGATGCATACCACCTGGACCAGGCCTTTGCACTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTCAGCCCCCGCTATCAGCATACCGTCACGCTGTATGCGAAAGGACTGACCTGCGAAGCCGATACACTGGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAATGAAAAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References