Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 7035469..7035983 Replicon chromosome
Accession NZ_CP073721
Organism Dactylosporangium roseum strain NRRL B-16295

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag Drose_RS33010 Protein ID WP_260725167.1
Coordinates 7035723..7035983 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag Drose_RS33005 Protein ID WP_260725166.1
Coordinates 7035469..7035726 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Drose_RS32985 7030780..7031541 - 762 Protein_6537 glycosyltransferase 87 family protein -
Drose_RS32990 (Drose_32745) 7031973..7034201 - 2229 WP_260725164.1 EAL domain-containing protein -
Drose_RS32995 (Drose_32750) 7034306..7034599 + 294 WP_259859533.1 metal-sensitive transcriptional regulator -
Drose_RS33000 (Drose_32755) 7034604..7035092 + 489 WP_260725165.1 hypothetical protein -
Drose_RS33005 (Drose_32760) 7035469..7035726 + 258 WP_260725166.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
Drose_RS33010 (Drose_32765) 7035723..7035983 + 261 WP_260725167.1 Txe/YoeB family addiction module toxin Toxin
Drose_RS33015 (Drose_32770) 7036561..7036782 + 222 WP_260725168.1 hypothetical protein -
Drose_RS33020 (Drose_32775) 7037863..7038585 + 723 WP_260729897.1 site-specific integrase -
Drose_RS33030 (Drose_32785) 7038837..7039391 - 555 WP_260725169.1 YqgE/AlgH family protein -
Drose_RS33035 (Drose_32790) 7039660..7040442 + 783 WP_260725170.1 S-methyl-5'-thioadenosine phosphorylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-70)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10187.58 Da        Isoelectric Point: 8.8832

>T200131 WP_260725167.1 NZ_CP073721:7035723-7035983 [Dactylosporangium roseum]
VKLSWTDLAWDDYLYWQTQDRKTLRRINALIADIKRDPDGPGIGKPELLRNNLAGLRSRRIDDEHRLVYAVTPDEVTIIS
CRYRYQ

Download         Length: 261 bp

>T200131 NZ_CP097716:225451-225558 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTCTGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9465.55 Da        Isoelectric Point: 4.7628

>AT200131 WP_260725166.1 NZ_CP073721:7035469-7035726 [Dactylosporangium roseum]
MTQAISASEARKSLFPLIEQVNNDHTPIEIVSKRGNAVLVSKEDWDAIVETNYLLRSPANAKHLMASVEQWRSGQATERD
LDSDA

Download         Length: 258 bp

>AT200131 NZ_CP097716:c225394-225339 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References