200130

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 6513335..6513900 Replicon chromosome
Accession NZ_CP073721
Organism Dactylosporangium roseum strain NRRL B-16295

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag Drose_RS30530 Protein ID WP_260724726.1
Coordinates 6513643..6513900 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag Drose_RS30525 Protein ID WP_260724725.1
Coordinates 6513335..6513622 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Drose_RS30495 (Drose_30260) 6509663..6510121 + 459 WP_260724720.1 peroxiredoxin -
Drose_RS30505 (Drose_30270) 6510599..6511333 + 735 WP_260724721.1 XRE family transcriptional regulator -
Drose_RS30510 (Drose_30275) 6511344..6511820 + 477 WP_260724722.1 NUDIX domain-containing protein -
Drose_RS30515 (Drose_30280) 6511813..6512277 + 465 WP_260724723.1 hypothetical protein -
Drose_RS30520 (Drose_30285) 6512242..6512787 - 546 WP_260724724.1 HD domain-containing protein -
Drose_RS30525 (Drose_30295) 6513335..6513622 + 288 WP_260724725.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
Drose_RS30530 (Drose_30300) 6513643..6513900 + 258 WP_260724726.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Drose_RS30535 (Drose_30305) 6513966..6514424 + 459 WP_260724727.1 hypothetical protein -
Drose_RS30540 (Drose_30310) 6514813..6516381 - 1569 WP_260724728.1 methyl-accepting chemotaxis protein -
Drose_RS30545 (Drose_30315) 6516479..6516943 + 465 WP_260724729.1 hypothetical protein -
Drose_RS30550 (Drose_30320) 6516947..6517726 - 780 WP_260724730.1 aldo/keto reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(28-80)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9580.94 Da        Isoelectric Point: 9.3846

>T200130 WP_260724726.1 NZ_CP073721:6513643-6513900 [Dactylosporangium roseum]
VKLTGPARRALETGLPEAIAWAAYTFVTERLPTNPHRLGGELDGPYEGMRSAQLGTYRVVYRIEEETRTVYVLSIRLRGD
VYGVR

Download         Length: 258 bp

>T200130 NZ_CP097716:224967-225074 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTCTGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10101.31 Da        Isoelectric Point: 4.3324

>AT200130 WP_260724725.1 NZ_CP073721:6513335-6513622 [Dactylosporangium roseum]
MTQILNVTDAKARLSELVAAVATTHDNVEITRNGEPAAVLVSFEELRALRETVAILSDAAAAADIREAEEDIAAGRLTDA
EDLGDVMRARRRGAA

Download         Length: 288 bp

>AT200130 NZ_CP097716:c224918-224855 [Escherichia coli]
GTCTAGATGCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References