Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 8688374..8688945 Replicon chromosome
Accession NZ_CP073720
Organism Dactylosporangium fulvum strain NRRL B-16292

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag Dfulv_RS39915 Protein ID WP_259858993.1
Coordinates 8688688..8688945 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag Dfulv_RS39910 Protein ID WP_259858992.1
Coordinates 8688374..8688661 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Dfulv_RS39895 (Dfulv_39895) 8686062..8686520 + 459 WP_259858990.1 peroxiredoxin -
Dfulv_RS39905 (Dfulv_39905) 8686803..8687366 + 564 WP_259858991.1 Uma2 family endonuclease -
Dfulv_RS39910 (Dfulv_39910) 8688374..8688661 + 288 WP_259858992.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
Dfulv_RS39915 (Dfulv_39915) 8688688..8688945 + 258 WP_259858993.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Dfulv_RS39920 (Dfulv_39920) 8688975..8689469 + 495 WP_259858994.1 hypothetical protein -
Dfulv_RS39925 (Dfulv_39925) 8689731..8689958 + 228 WP_259858995.1 Uma2 family endonuclease -
Dfulv_RS39930 (Dfulv_39930) 8690285..8690542 + 258 WP_259858996.1 type II toxin-antitoxin system RelE/ParE family toxin -
Dfulv_RS39935 (Dfulv_39935) 8690685..8691686 + 1002 WP_259858997.1 NADP-dependent oxidoreductase -
Dfulv_RS39940 (Dfulv_39940) 8691832..8692341 - 510 WP_259858998.1 hypothetical protein -
Dfulv_RS39945 (Dfulv_39945) 8693261..8693899 + 639 WP_259858999.1 transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(28-80)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9603.98 Da        Isoelectric Point: 9.3852

>T200128 WP_259858993.1 NZ_CP073720:8688688-8688945 [Dactylosporangium fulvum]
VKLTGPARRALETGLPEAVAWAAYTFITERLPTNPHRLGGELEGPYEGMRSAHLGTYRVVYRIDEETRTVYVLSIRLRGD
VYGIR

Download         Length: 258 bp

>T200128 NZ_CP097716:167621-167806 [Escherichia coli]
GTGAAAAGTGCAGACGTGATCGCCATCCTGAAGCAGCATGGCTGGGAACATATTCGAACCCGTGGCAGTCATCATCAGTT
CCGCCACCCTGTTCATCCGGGTCTGGTGACGGTTCCGCACCCTAAAAAAGATATTAAGCCCGGTACGCTGGCGCAAATTG
GGCGTCAGGCTGGTTTAACATTTTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10115.34 Da        Isoelectric Point: 4.3324

>AT200128 WP_259858992.1 NZ_CP073720:8688374-8688661 [Dactylosporangium fulvum]
MTQILNVTDAKARLSELVAAVATTHDNVEITRNGEPAAVLVSFEELRALRETVAILSDAAAVADIREAEEDIAAGRVTDA
EDLGDVMRARRRGAA

Download         Length: 288 bp

>AT200128 NZ_CP097716:167823-168233 [Escherichia coli]
ATGTTTTATCCCGCCTATATCCACAGTGATCCTGACGGCAGCGCCAGCGGTTTTTTCCCTGATGTTCCAGGCTGTTATTT
TGCTGGTGATACGCTGGACAACGCTTTCCAGGATGCGCGAAGTGCACTGGCCGCGCACTTCGAAACCTTATGCGAGATGG
ATGAAGAGTTGCCGCTTCCAGGCTCTGTGGAAACACATCTGGTCCAGCGTGCGCAGGACTTTATTGGCGGGCAATGGTTG
CTGGTGGATATCAATATGAATCAGTTCGAAGGTCGGGCTGAACGTATCAATATTACGATGCCGAAAAGGTTACTGAACAA
GATTGATACCTACGTGCGCAATAACCCAGACTACGCCAACAGAAGTGCGTTTCTGGCAGAAGCTGCCCGGCGTGTATTGC
CGGGCGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References