Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 4513556..4514235 Replicon chromosome
Accession NZ_CP073677
Organism Cupriavidus sp. KK10

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KB879_RS21040 Protein ID WP_211979716.1
Coordinates 4513807..4514235 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KB879_RS21035 Protein ID WP_041228808.1
Coordinates 4513556..4513810 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 14961.24 Da        Isoelectric Point: 5.1006

>T200025 WP_211979716.1 NZ_CP073677:4513807-4514235 [Cupriavidus sp. KK10]
MIVLDTNVISEAMKPEPADSVRCWLNDQAAETLYLSSVTLAELLFGIGALPAGRRRAMLAAALDGLVTLFEGRILPFDTN
AARHYAELATAARSRGRGLPTPDGHIAAIAAANGMIVATRDVSPFEAAGLQVLNPWLAPPPS

Download         Length: 429 bp

>T200025 NZ_CP097688:4275487-4275705 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9175.52 Da        Isoelectric Point: 7.0159

>AT200025 WP_041228808.1 NZ_CP073677:4513556-4513810 [Cupriavidus sp. KK10]
MPILTVRNVPDDVHRALRVRAAQNGRSTEAEVREILASAVMPQKRVRLGDALAMLGREIGLSNADVEAIEQGKDKAAAEP
VRFE

Download         Length: 255 bp

>AT200025 NZ_CP097688:4275086-4275460 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References