Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3222147..3222805 Replicon chromosome
Accession NZ_CP073677
Organism Cupriavidus sp. KK10

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KB879_RS15185 Protein ID WP_211981994.1
Coordinates 3222147..3222557 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KB879_RS15190 Protein ID WP_041228698.1
Coordinates 3222554..3222805 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

SpoVT-AbrB domain

(8-55)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 14500.92 Da        Isoelectric Point: 7.2774

>T200023 WP_211981994.1 NZ_CP073677:c3222557-3222147 [Cupriavidus sp. KK10]
MTRYMLDTNIVSHLLRAHPAVVARVTAAPMAALCLSAITGAELMYGLAKRPGAARLARAVDELLRRVEVLPWTPSVMVGY
GETRAALESQGQPMGALDLLIAAHALETGAVLVTNDQAFRRVPGLVVEDWSVPTGN

Download         Length: 411 bp

>T200023 NZ_CP097688:2107653-2107755 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9164.27 Da        Isoelectric Point: 6.3139

>AT200023 WP_041228698.1 NZ_CP073677:c3222805-3222554 [Cupriavidus sp. KK10]
VSTTAKIFTTGRSQAVRLPQEFRFAEREVYIRRDPSTGDVILSRRPESWDGFLAAIKDSAVPADFLAGRAQGEQARDPLA
GLE

Download         Length: 252 bp

>AT200023 NZ_CP097688:c2107762-2107617 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References