Detailed information of TA system TA199845

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ygfYX/Cpta(toxin)
• Location: 2619081..2619726
• Replicon: chromosome
• Accession: NZ_CP073587
• Organism: Shewanella yunxiaonensis strain FJAT-54481

Toxin (Protein)

• Gene name: ygfX
• Uniprot ID: -
• Locus tag: KDN34_RS11965
• Protein ID: WP_212593998.1
• Coordinates: 2619081..2619479 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: ygfY
• Uniprot ID: -
• Locus tag: KDN34_RS11970
• Protein ID: WP_212596636.1
• Coordinates: 2619487..2619726 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KDN34_RS11940 (KDN34_11940)	2614622..2615113	-	492	WP_212593993.1	SoxR reducing system RseC family protein	-
KDN34_RS11945 (KDN34_11945)	2615124..2616056	-	933	WP_212593994.1	MucB/RseB C-terminal domain-containing protein	-
KDN34_RS11950 (KDN34_11950)	2616066..2616674	-	609	WP_212593995.1	RseA family anti-sigma factor	-
KDN34_RS11955 (KDN34_11955)	2616702..2617280	-	579	WP_212593996.1	RNA polymerase sigma factor RpoE	-
KDN34_RS11960 (KDN34_11960)	2617483..2619093	+	1611	WP_212593997.1	L-aspartate oxidase	-
KDN34_RS11965 (KDN34_11965)	2619081..2619479	-	399	WP_212593998.1	hypothetical protein	Toxin
KDN34_RS11970 (KDN34_11970)	2619487..2619726	-	240	WP_212596636.1	succinate dehydrogenase assembly factor 2	Antitoxin
KDN34_RS11975 (KDN34_11975)	2619804..2620712	-	909	WP_212593999.1	transcriptional activator NhaR	-
KDN34_RS11980 (KDN34_11980)	2620728..2621111	-	384	WP_212594000.1	hypothetical protein	-
KDN34_RS11985 (KDN34_11985)	2621108..2622283	-	1176	WP_212594001.1	Na+/H+ antiporter NhaA	-
KDN34_RS11990 (KDN34_11990)	2622402..2623196	-	795	WP_212594002.1	thymidylate synthase	-
KDN34_RS11995 (KDN34_11995)	2623196..2624023	-	828	WP_212594003.1	prolipoprotein diacylglyceryl transferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-126)

Antitoxin

• Flavinator of succinate dehydrogenase (4-75)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 15530.00 Da
• Isoelectric Point: 5.7606

>T199845 WP_212593998.1 NZ_CP073587:c2619479-2619081 [Shewanella yunxiaonensis]
VKSSFGQYLALMVLAAVCLLSFCFWPDLDYLFYQPLRWLMVTTLIGYFSVRLWRLRYWQLEFWLAGNGGGQFETGDSFDV
AEPVMVTPWLVSFSCQLPTGFRRLYLFSDMFDDTDYRHLCRLLLNRNSPYSG

Nucleotide

• Length: 399 bp

>T199845 NZ_CP097626:c4805419-4804886 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGTGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAAGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9203.68 Da
• Isoelectric Point: 6.9208

>AT199845 WP_212596636.1 NZ_CP073587:c2619726-2619487 [Shewanella yunxiaonensis]
MNYARVKWACRRGMLELDVLFQPFVEKYYQDLTDTDKATFVRLLECEDPQLFAWFMGHAKCSDPQLADMVAKVRGRAAP

Nucleotide

• Length: 240 bp

>AT199845 NZ_CP097626:c4805696-4805430 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA