Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1375531..1376047 Replicon chromosome
Accession NZ_CP073578
Organism Photobacterium sp. GJ3

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag KDD30_RS06175 Protein ID WP_211648201.1
Coordinates 1375531..1375800 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag KDD30_RS06180 Protein ID WP_211648209.1
Coordinates 1375790..1376047 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KDD30_RS06160 (KDD30_06160) 1370592..1372127 - 1536 WP_211648169.1 M28 family metallopeptidase -
KDD30_RS06165 (KDD30_06165) 1372588..1373469 - 882 WP_211648177.1 lateral flagellin LafA -
KDD30_RS06170 (KDD30_06170) 1373829..1374707 - 879 WP_211648186.1 lateral flagellin LafA -
KDD30_RS24470 1375330..1375440 + 111 Protein_1189 IS110 family transposase -
KDD30_RS06175 (KDD30_06175) 1375531..1375800 - 270 WP_211648201.1 Txe/YoeB family addiction module toxin Toxin
KDD30_RS06180 (KDD30_06180) 1375790..1376047 - 258 WP_211648209.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KDD30_RS06185 (KDD30_06185) 1376330..1377136 - 807 WP_211648211.1 hypothetical protein -
KDD30_RS06190 (KDD30_06190) 1377129..1379152 - 2024 Protein_1193 flagellar biosynthesis protein FlhA -
KDD30_RS06195 (KDD30_06195) 1379243..1380373 - 1131 WP_211648225.1 flagellar biosynthesis protein FlhB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(10-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10657.09 Da        Isoelectric Point: 9.4092

>T199841 WP_211648201.1 NZ_CP073578:c1375800-1375531 [Photobacterium sp. GJ3]
MSHSQRLLTWTDEAWGDYLYWQTQDKKTLKRINKLINDVKRSPFEGIGKPEPLKENLSGFWSRRIDDTNRLVYAVDHQAI
TIISCRYHY

Download         Length: 270 bp

>T199841 NZ_CP097626:877746-878153 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCGTGC
GCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCCGAA
TGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGGACA
GCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGGCGC
AGGAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9559.63 Da        Isoelectric Point: 4.5700

>AT199841 WP_211648209.1 NZ_CP073578:c1376047-1375790 [Photobacterium sp. GJ3]
MKIVSFTEARNSLKAVLDGVVNDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPENAEHLNRSIAQYRAGQTTTRD
LIDES

Download         Length: 258 bp

>AT199841 NZ_CP097626:877499-877765 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References