Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-MqsA
Location 3679544..3680285 Replicon chromosome
Accession NZ_CP073356
Organism Proteus terrae subsp. cibarius strain SDQ8C180-2T

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KDN45_RS16800 Protein ID WP_223672638.1
Coordinates 3679544..3679972 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KDN45_RS16805 Protein ID WP_075671318.1
Coordinates 3679965..3680285 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KDN45_RS16785 (KDN45_16700) 3675624..3676208 - 585 WP_075671324.1 DNA-3-methyladenine glycosylase I -
KDN45_RS16790 (KDN45_16705) 3676447..3677352 + 906 WP_004246832.1 glycine--tRNA ligase subunit alpha -
KDN45_RS16795 (KDN45_16710) 3677362..3679434 + 2073 WP_075671322.1 glycine--tRNA ligase subunit beta -
KDN45_RS16800 (KDN45_16715) 3679544..3679972 + 429 WP_223672638.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KDN45_RS16805 (KDN45_16720) 3679965..3680285 + 321 WP_075671318.1 helix-turn-helix domain-containing protein Antitoxin
KDN45_RS16810 (KDN45_16725) 3680352..3680672 - 321 WP_075671316.1 hypothetical protein -
KDN45_RS16815 (KDN45_16730) 3680778..3682064 - 1287 WP_075671314.1 DUF3748 domain-containing protein -
KDN45_RS16820 (KDN45_16735) 3682201..3682818 + 618 WP_006534609.1 trimeric intracellular cation channel family protein -
KDN45_RS16825 (KDN45_16740) 3683124..3683747 + 624 WP_006534608.1 guanylate kinase -
KDN45_RS16830 (KDN45_16745) 3683802..3684077 + 276 WP_004246820.1 DNA-directed RNA polymerase subunit omega -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(15-139)

Antitoxin

Cro/C1-type helix-turn-helix domain

(50-96)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15862.55 Da        Isoelectric Point: 10.1197

>T199745 WP_223672638.1 NZ_CP073356:3679544-3679972 [Proteus terrae subsp. cibarius]
VVKFTIVKTTTGEVMVIYKTKMFKNSFKKMPINDAALIDIANEVYAGHFEADLGGGIIKKRICIHGKGKSSGIRTIIFYK
QGSNLFFADGWKKSHLSAKKSKEITDDELESYKDLAKDLFSATKNKIDKMVALGLLTEVKHD

Download         Length: 429 bp

>T199745 NZ_CP097557:c149462-149181 [Pseudomonas aeruginosa]
ATGAGCCTGAAGTGGACCCGCAAGGCGGCCGCCGACCTGGACGCCATCTACGACCATTACGTCGTGCTGATCGGCCCGGA
AAAAGCCCTGAAAGCCGTCCAGGACATCGTCGAGCAGGTGAAACCGCTGCAGCAGGTAGCCAACCAGGGGGCAGGGCGGC
CCAGCGAGGTGCCAGGCGTACGCACCCTGACCCTGGAGCGCTGGCCGTTCAGCGCCCCTTTTCGGGTAAAAGGCAAGGAA
ATCCAGATTTTGCGCATCGACAGGGTCGAAATTACCCCCTGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 12068.99 Da        Isoelectric Point: 10.0482

>AT199745 WP_075671318.1 NZ_CP073356:3679965-3680285 [Proteus terrae subsp. cibarius]
MTDKMQEMLKFAQEMEVAGITDGESARRIAARIKAKELKERYAHLTPMNGEDIKRIREQNNISQSSLALILNMTKESVSK
WERNEIKPNGAALRLLNLIDNKAISI

Download         Length: 321 bp

>AT199745 NZ_CP097557:c149686-149459 [Pseudomonas aeruginosa]
ATGAGCACCGTAGTCTCGTTCCGCGCCGATGACGCCCTGGTCGCGGCCCTCGACGAACTGGCCCGCGCCACCCACCGCGA
CCGCCCGTATCACCTGCGGCAGGCGCTCGCGCAGTACCTGGAAAGGCAGCAGTGGCAGGTCGCTGCCATCGATGAAGGCT
TGGCCGATGCCAATGCCGGTCGCCTGCTGGAACACACCGAGATCGAGAAGCGCTGGGGGCTGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References