Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2002151..2002296 Replicon chromosome
Accession NZ_CP073351
Organism Klebsiella pneumoniae strain CP19

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2002187..2002289 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2002151..2002296 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBT94_RS09815 1997281..1999341 + 2061 WP_004151449.1 oligopeptidase B -
KBT94_RS09820 1999345..2000004 - 660 WP_002911407.1 exodeoxyribonuclease X -
KBT94_RS09825 2000083..2000313 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KBT94_RS09830 2000426..2000800 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KBT94_RS09835 2000804..2001673 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
KBT94_RS09840 2001690..2002028 + 339 WP_002911404.1 YebY family protein -
- 2002151..2002296 - 146 - - Antitoxin
- 2002187..2002289 + 103 - - Toxin
KBT94_RS09845 2002664..2002807 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KBT94_RS09850 2002912..2003880 - 969 WP_004151446.1 VirK/YbjX family protein -
KBT94_RS09855 2004037..2004690 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KBT94_RS09860 2004687..2004878 - 192 WP_002911395.1 YebW family protein -
KBT94_RS09865 2004976..2005215 - 240 WP_002911393.1 YebV family protein -
KBT94_RS09870 2005331..2006764 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T199725 NZ_CP073351:2002187-2002289 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT199725 NZ_CP073351:c2002296-2002151 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References