Detailed information of TA system TA199716

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-YefM
• Location: 3397917..3398488
• Replicon: chromosome
• Accession: NZ_CP073343
• Organism: Marinomonas rhizomae strain MB12-11

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: KDW99_RS16035
• Protein ID: WP_255826109.1
• Coordinates: 3397917..3398228 (-)
• Length: 104 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: KDW99_RS16040
• Protein ID: WP_255826110.1
• Coordinates: 3398228..3398488 (-)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KDW99_RS16015 (KDW99_15970)	3393841..3394719	-	879	WP_255829306.1	ABC transporter substrate-binding protein	-
KDW99_RS16020 (KDW99_15975)	3395047..3395994	-	948	WP_255826106.1	AEC family transporter	-
KDW99_RS16025 (KDW99_15980)	3396050..3396952	-	903	WP_255826107.1	LysR substrate-binding domain-containing protein	-
KDW99_RS16030 (KDW99_15985)	3397079..3397777	+	699	WP_255826108.1	pirin family protein	-
KDW99_RS16035 (KDW99_15990)	3397917..3398228	-	312	WP_255826109.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
KDW99_RS16040 (KDW99_15995)	3398228..3398488	-	261	WP_255826110.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
KDW99_RS16045 (KDW99_16000)	3399127..3399408	-	282	WP_255826111.1	hypothetical protein	-
KDW99_RS16050 (KDW99_16005)	3399405..3399869	-	465	WP_255826112.1	DUF2778 domain-containing protein	-
KDW99_RS16055 (KDW99_16010)	3400000..3400617	-	618	WP_255826113.1	HEPN domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-92)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-68)

Sequences

Toxin

Protein

• Length: 104 a.a.
• Molecular weight: 11823.64 Da
• Isoelectric Point: 9.5908

>T199716 WP_255826109.1 NZ_CP073343:c3398228-3397917 [Marinomonas rhizomae]
MSAIYYLTPDAKSDLVGVHRFTLANWGETQSKQYLSGIRQTIRLLAEAPSLGKSRSEVRENVFSFPYGSHVIYYIEDKNY
IVVFAVLHKSMVPFIHLSDRKLL

Nucleotide

• Length: 312 bp

>T199716 NZ_CP097529:2780561-2780998 [Pseudomonas putida]
GTGATTTTGTGGCGAATCAGCGCCTATGCAGACTTGAGCGGTACGGGGGGCTTGCGTGTAAGTGGCCGCTGGCACCAGGC
GGGTCGGCCGGTGGTGTATGCCGCCACCAGCCCTCCTGGGGCGATGCTGGAAGTGTTGGTGCACCTGGAGATCGACCCCG
AGGATTTCCCTACCACCATGCGCTTGCTTCGCATCGAACTGCCCGACACGGTTTCCCAGGCGCAGTTGCCCGCTTTGCAG
CCCGGCTGGTCTGCTCAGCCTGAGTTGACCCGAACGCTGGGCAATCGCTTTCTGGATGACTGTTCGGCATTGCTGCTGCC
GGTGCCAAGCGCGATCATGCCCAGCACCACCAATTACCTGTTCAACCCACGGCACCCGCAGGCGCAGAGCGCGAAAATCC
AGGTTGAGGATTTCACGCCGGACAGCCGCCTGTTCTAG

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9503.82 Da
• Isoelectric Point: 4.5680

>AT199716 WP_255826110.1 NZ_CP073343:c3398488-3398228 [Marinomonas rhizomae]
MNTISANEAKTHFGDLLLNAQKSPVQISKNGKPVAVVISVDEYESIEAMKLYLLQNKAAQAMKDISKRDLVAGEAFFNEL
EEGLYD

Nucleotide

• Length: 261 bp

>AT199716 NZ_CP097529:2780115-2780564 [Pseudomonas putida]
ATGCTTGCCGAAGTGCTTCGCGACAACGGTTACCACGAGTACCGGGCGCGCCTGCAGGCGCTGCTGGACATTCCCGAGCT
TGCCAGCGATTTCGAAATCCACACCCGCATCACCGATGGTTTTGCCGCCACCTGGTTGGTAAAGCTGACCGAACGCGGTG
TGCTCACGCCGGTGGAGCGCGACCAGATCATCCCGCTGCGCACCCTCAAATCCCGTATCGAGCGTGACCAACCGCTGACC
GTGGATGAGAGCGATCGGCTGTTCCGCTCGGCCCACATCACCGCCATGGCCGAGGCCGTGTTCGGTGAAGCGGGCAAGGC
CAAACGCTGGCTTTCCAAGCCCAAGGAACGCTTCTCGGGGCTGACGCCGATGCAGATGCTCACCACCCAGCAAGGCACCA
CGCAGGTCGAAGAAATGCTGCTGCAGATTGCCGAGGGCTATGGCCTGTGA