Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 3397917..3398488 Replicon chromosome
Accession NZ_CP073343
Organism Marinomonas rhizomae strain MB12-11

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag KDW99_RS16035 Protein ID WP_255826109.1
Coordinates 3397917..3398228 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag KDW99_RS16040 Protein ID WP_255826110.1
Coordinates 3398228..3398488 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KDW99_RS16015 (KDW99_15970) 3393841..3394719 - 879 WP_255829306.1 ABC transporter substrate-binding protein -
KDW99_RS16020 (KDW99_15975) 3395047..3395994 - 948 WP_255826106.1 AEC family transporter -
KDW99_RS16025 (KDW99_15980) 3396050..3396952 - 903 WP_255826107.1 LysR substrate-binding domain-containing protein -
KDW99_RS16030 (KDW99_15985) 3397079..3397777 + 699 WP_255826108.1 pirin family protein -
KDW99_RS16035 (KDW99_15990) 3397917..3398228 - 312 WP_255826109.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KDW99_RS16040 (KDW99_15995) 3398228..3398488 - 261 WP_255826110.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KDW99_RS16045 (KDW99_16000) 3399127..3399408 - 282 WP_255826111.1 hypothetical protein -
KDW99_RS16050 (KDW99_16005) 3399405..3399869 - 465 WP_255826112.1 DUF2778 domain-containing protein -
KDW99_RS16055 (KDW99_16010) 3400000..3400617 - 618 WP_255826113.1 HEPN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11823.64 Da        Isoelectric Point: 9.5908

>T199716 WP_255826109.1 NZ_CP073343:c3398228-3397917 [Marinomonas rhizomae]
MSAIYYLTPDAKSDLVGVHRFTLANWGETQSKQYLSGIRQTIRLLAEAPSLGKSRSEVRENVFSFPYGSHVIYYIEDKNY
IVVFAVLHKSMVPFIHLSDRKLL

Download         Length: 312 bp

>T199716 NZ_CP097529:2780561-2780998 [Pseudomonas putida]
GTGATTTTGTGGCGAATCAGCGCCTATGCAGACTTGAGCGGTACGGGGGGCTTGCGTGTAAGTGGCCGCTGGCACCAGGC
GGGTCGGCCGGTGGTGTATGCCGCCACCAGCCCTCCTGGGGCGATGCTGGAAGTGTTGGTGCACCTGGAGATCGACCCCG
AGGATTTCCCTACCACCATGCGCTTGCTTCGCATCGAACTGCCCGACACGGTTTCCCAGGCGCAGTTGCCCGCTTTGCAG
CCCGGCTGGTCTGCTCAGCCTGAGTTGACCCGAACGCTGGGCAATCGCTTTCTGGATGACTGTTCGGCATTGCTGCTGCC
GGTGCCAAGCGCGATCATGCCCAGCACCACCAATTACCTGTTCAACCCACGGCACCCGCAGGCGCAGAGCGCGAAAATCC
AGGTTGAGGATTTCACGCCGGACAGCCGCCTGTTCTAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9503.82 Da        Isoelectric Point: 4.5680

>AT199716 WP_255826110.1 NZ_CP073343:c3398488-3398228 [Marinomonas rhizomae]
MNTISANEAKTHFGDLLLNAQKSPVQISKNGKPVAVVISVDEYESIEAMKLYLLQNKAAQAMKDISKRDLVAGEAFFNEL
EEGLYD

Download         Length: 261 bp

>AT199716 NZ_CP097529:2780115-2780564 [Pseudomonas putida]
ATGCTTGCCGAAGTGCTTCGCGACAACGGTTACCACGAGTACCGGGCGCGCCTGCAGGCGCTGCTGGACATTCCCGAGCT
TGCCAGCGATTTCGAAATCCACACCCGCATCACCGATGGTTTTGCCGCCACCTGGTTGGTAAAGCTGACCGAACGCGGTG
TGCTCACGCCGGTGGAGCGCGACCAGATCATCCCGCTGCGCACCCTCAAATCCCGTATCGAGCGTGACCAACCGCTGACC
GTGGATGAGAGCGATCGGCTGTTCCGCTCGGCCCACATCACCGCCATGGCCGAGGCCGTGTTCGGTGAAGCGGGCAAGGC
CAAACGCTGGCTTTCCAAGCCCAAGGAACGCTTCTCGGGGCTGACGCCGATGCAGATGCTCACCACCCAGCAAGGCACCA
CGCAGGTCGAAGAAATGCTGCTGCAGATTGCCGAGGGCTATGGCCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References