Detailed information of TA system TA199715

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 2591480..2592008
• Replicon: chromosome
• Accession: NZ_CP073343
• Organism: Marinomonas rhizomae strain MB12-11

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: KDW99_RS12330
• Protein ID: WP_255825113.1
• Coordinates: 2591721..2592008 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: KDW99_RS12325
• Protein ID: WP_255825111.1
• Coordinates: 2591480..2591731 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KDW99_RS12310 (KDW99_12270)	2586983..2589328	-	2346	WP_255825105.1	xanthine dehydrogenase molybdopterin binding subunit	-
KDW99_RS12315 (KDW99_12275)	2589321..2590820	-	1500	WP_255825107.1	xanthine dehydrogenase small subunit	-
KDW99_RS12320 (KDW99_12280)	2591066..2591368	+	303	WP_255825109.1	cupin domain-containing protein	-
KDW99_RS12325 (KDW99_12285)	2591480..2591731	+	252	WP_255825111.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
KDW99_RS12330 (KDW99_12290)	2591721..2592008	+	288	WP_255825113.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
KDW99_RS12335 (KDW99_12295)	2592214..2593209	+	996	WP_255825115.1	ABC transporter substrate-binding protein	-
KDW99_RS12340 (KDW99_12300)	2593214..2594020	+	807	WP_212915632.1	ABC transporter ATP-binding protein	-
KDW99_RS12345 (KDW99_12305)	2593998..2594792	+	795	WP_212915633.1	ABC transporter permease	-
KDW99_RS12350 (KDW99_12310)	2594807..2595283	+	477	WP_255825120.1	nucleoside deaminase	-
KDW99_RS12355 (KDW99_12315)	2595408..2596394	+	987	WP_255825122.1	2-oxoglutarate and iron-dependent oxygenase domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-71)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10995.98 Da
• Isoelectric Point: 10.5236

>T199715 WP_255825113.1 NZ_CP073343:2591721-2592008 [Marinomonas rhizomae]
VTYKLKFLPAALKEWRKLAPQIQTQFKKKLAERLENPHVPASKLRGYDSVYKIKLRTSGYRLAYEVIDDEIVIYILAIGK
RDKDAVYKKLASRAG

Nucleotide

• Length: 288 bp

>T199715 NZ_CP097529:c1777998-1777720 [Pseudomonas putida]
ATGATTCGAAGCTTTAGCTGTGCCGACACGGAAGCGCTCTTCACAACGGGAAAGACACGGCGCGGGTCAGATATCAAGTC
AGTCGCGGAGCGCAAGCTGGCCATGCTCGATGCCGCAACAGAGTTGCGAGACCTTAGGTCGCCACCTGGCAATCGCCTCG
AGTCACTGAGCGGCAACCGCGCCGACCAGCACAGTATCCGTGTAAATGACCAATGGCGGTTGTGCTTCACCTGGACAGAG
CACGGGCCAGTTAACGTTGAAATTGTCGATTACCACTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9001.34 Da
• Isoelectric Point: 4.5338

>AT199715 WP_255825111.1 NZ_CP073343:2591480-2591731 [Marinomonas rhizomae]
MRQVLANYTASISELKKNPTALLNESGGSAIAILNHNKPAAYLVPAESYELLMEMADDIELAKLVEARRTDLSKAIEVSL
GDL

Nucleotide

• Length: 252 bp

>AT199715 NZ_CP097529:c1777711-1777412 [Pseudomonas putida]
ATGCTCAAGAACGGTATGCGTCCAATCCATCCGGGTGAAATCCTGCGGGAGGAGTTCCAGAAGGAAATGGGCTTCAGCGC
CGCGGCTCTGGCCAGGGCGTTGGGTGTAGCAACGCCAACCGTCAACAACATCCTGCGCGAACGGGGCGGTGTTTCCGCCG
ACATGGCACTGCGCCTGTCCATCTGCCTGGACACCACCCCTGAGTTCTGGCTCAACCTGCAGACGGCCTTCGATCTGCGC
ACAGCCGAACAGCAACACGGCGATGAGATCATCGGGTCGGTCCAGCGTCTGGTCGCTTGA