Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2070331..2070476 Replicon chromosome
Accession NZ_CP073302
Organism Klebsiella pneumoniae strain SW1780

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2070367..2070469 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2070331..2070476 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KCX81_RS10205 (KCX81_10205) 2065461..2067521 + 2061 WP_004151449.1 oligopeptidase B -
KCX81_RS10210 (KCX81_10210) 2067525..2068184 - 660 WP_002911407.1 exodeoxyribonuclease X -
KCX81_RS10215 (KCX81_10215) 2068263..2068493 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KCX81_RS10220 (KCX81_10220) 2068606..2068980 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KCX81_RS10225 (KCX81_10225) 2068984..2069853 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
KCX81_RS10230 (KCX81_10230) 2069870..2070208 + 339 WP_002911404.1 YebY family protein -
- 2070331..2070476 - 146 - - Antitoxin
- 2070367..2070469 + 103 - - Toxin
KCX81_RS10235 (KCX81_10235) 2070844..2070987 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KCX81_RS10240 (KCX81_10240) 2071092..2072060 - 969 WP_004151446.1 VirK/YbjX family protein -
KCX81_RS10245 (KCX81_10245) 2072217..2072870 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KCX81_RS10250 (KCX81_10250) 2072867..2073058 - 192 WP_002911395.1 YebW family protein -
KCX81_RS10255 (KCX81_10255) 2073156..2073395 - 240 WP_002911393.1 YebV family protein -
KCX81_RS10260 (KCX81_10260) 2073511..2074944 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T199670 NZ_CP073302:2070367-2070469 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT199670 NZ_CP073302:c2070476-2070331 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References