Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX-ArgA
Location 5108181..5109000 Replicon chromosome
Accession NZ_CP073236
Organism Klebsiella pasteurii strain Sb-24

Toxin (Protein)


Gene name yjhX Uniprot ID -
Locus tag KCG39_RS23920 Protein ID WP_004129235.1
Coordinates 5108181..5108438 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag KCG39_RS23925 Protein ID WP_142446300.1
Coordinates 5108449..5109000 (+) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KCG39_RS23905 (KCG39_23905) 5103947..5104723 - 777 WP_004129229.1 Uxu operon transcriptional regulator -
KCG39_RS23910 (KCG39_23910) 5104861..5106336 - 1476 WP_112165899.1 fructuronate reductase -
KCG39_RS23915 (KCG39_23915) 5106413..5107597 - 1185 WP_004129234.1 mannonate dehydratase -
KCG39_RS23920 (KCG39_23920) 5108181..5108438 + 258 WP_004129235.1 YjhX family toxin Toxin
KCG39_RS23925 (KCG39_23925) 5108449..5109000 + 552 WP_142446300.1 N-acetyltransferase Antitoxin
KCG39_RS27820 5109114..5109473 + 360 Protein_4693 class I SAM-dependent methyltransferase -
KCG39_RS27825 5109900..5110646 + 747 WP_117085590.1 class I SAM-dependent methyltransferase -
KCG39_RS23935 (KCG39_23935) 5110864..5111751 - 888 WP_142446299.1 DMT family transporter -
KCG39_RS23940 (KCG39_23940) 5111871..5112779 + 909 WP_087828276.1 transcriptional regulator GcvA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(25-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9568.07 Da        Isoelectric Point: 11.1381

>T199602 WP_004129235.1 NZ_CP073236:5108181-5108438 [Klebsiella pasteurii]
MNLSRQEQRTLHVLAKGGRIAHVRDTSGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

>T199602 NZ_CP097419:c3110055-3109837 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20049.96 Da        Isoelectric Point: 7.5099

>AT199602 WP_142446300.1 NZ_CP073236:5108449-5109000 [Klebsiella pasteurii]
MTNHSFTFHVASEGDTDDILNVETRAFGYSKEARLVASLLNDESACPTLSLLARHNGKAVGHILFTRAMFKGEPDSPMMH
ILAPLAVVPEYQGAGVGGALIRHGIEQLKAIGSQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEAHKACWMLQRLSS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp

>AT199602 NZ_CP097419:c3110456-3110082 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References