Detailed information of TA system TA199579

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii(toxin)
• Location: 2958374..2959850
• Replicon: chromosome
• Accession: NZ_CP073110
• Organism: Agrobacterium rhizogenes strain A4

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: EML492_RS14830
• Protein ID: WP_034516990.1
• Coordinates: 2958374..2959240 (-)
• Length: 289 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: EML492_RS14835
• Protein ID: WP_034516992.1
• Coordinates: 2959233..2959850 (-)
• Length: 206 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EML492_RS14815 (EML492_14815)	2954719..2955390	-	672	WP_034516986.1	invasion associated locus B family protein	-
EML492_RS14820 (EML492_14820)	2955576..2955947	-	372	WP_234711812.1	DUF746 domain-containing protein	-
EML492_RS33835	2956053..2956208	+	156	WP_229202628.1	hypothetical protein	-
EML492_RS14825 (EML492_14825)	2956601..2957995	+	1395	WP_034516988.1	hypothetical protein	-
EML492_RS14830 (EML492_14830)	2958374..2959240	-	867	WP_034516990.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
EML492_RS14835 (EML492_14835)	2959233..2959850	-	618	WP_034516992.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
EML492_RS14840 (EML492_14840)	2960068..2960208	-	141	WP_153511264.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (38-260)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (16-55)

Sequences

Toxin

Protein

• Length: 289 a.a.
• Molecular weight: 32351.95 Da
• Isoelectric Point: 5.2615

>T199579 WP_034516990.1 NZ_CP073110:c2959240-2958374 [Agrobacterium rhizogenes]
MAKEIKNIGASVRARLLQLAKASGQSFDLVLTRFALERLLFRLSRSSHADRFVLKGAMLMMSWFDDPHRGTRDLDLLGFG
DPSAELMLATFREILAQDASDGVEFDADALRVDRIREELEYGGLRLRTTASISGARISLTIDIGFGDALEPGTEELDYPS
MLDFPMPRLRGYARETVIAEKFQAMVALGRANTRMKDFYDIWILSRSFDFSNDRLVRAITGTFERRETPIPTVLPDALTE
AFAQDQQKQRQWRAFVEDVAHNPGELMDVITDIAGFLMPHAAAASRGK

Nucleotide

• Length: 867 bp

>T199579 NZ_CP097411:c5291436-5291053 [Klebsiella pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin

Protein

• Length: 206 a.a.
• Molecular weight: 22434.05 Da
• Isoelectric Point: 10.2836

>AT199579 WP_034516992.1 NZ_CP073110:c2959850-2959233 [Agrobacterium rhizogenes]
MPESISQRQIAHALLTARGIARLVELRDAGVTAATMSRMERDGEVLRLARGLYQLSDAPLDANHSLAEAAKRLPKGVVCL
VSALAFHGLTDQLPKQVWLAIGRKDWAPKPDSTPIRIVRFTDRLLNESVETHVVEGVPVKVFGIVKTIADCFRYRNKIGL
SVAIEGLQEVLRQRKATPGEIARQAERGGVATVIRPYIEALTANG

Nucleotide

• Length: 618 bp

>AT199579 NZ_CP097411:c5291678-5291436 [Klebsiella pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA