199572

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 332502..332994 Replicon chromosome
Accession NZ_CP073084
Organism Streptococcus oriscaviae strain HKU75

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag INT76_RS01640 Protein ID WP_212571486.1
Coordinates 332502..332759 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag INT76_RS01645 Protein ID WP_212571488.1
Coordinates 332743..332994 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
INT76_RS01615 (INT76_01615) 327513..328031 + 519 WP_212571476.1 AAA family ATPase -
INT76_RS01620 (INT76_01620) 328150..329220 + 1071 WP_212571478.1 tyrosine recombinase XerS -
INT76_RS01625 (INT76_01625) 329270..330781 - 1512 WP_212571480.1 phosphomannomutase/phosphoglucomutase -
INT76_RS01630 (INT76_01630) 330857..331798 - 942 WP_212571482.1 sensor histidine kinase -
INT76_RS01635 (INT76_01635) 331795..332463 - 669 WP_212571484.1 response regulator transcription factor -
INT76_RS01640 (INT76_01640) 332502..332759 - 258 WP_212571486.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
INT76_RS01645 (INT76_01645) 332743..332994 - 252 WP_212571488.1 DUF6290 family protein Antitoxin
INT76_RS01650 (INT76_01650) 333087..335057 - 1971 WP_212571489.1 FtsX-like permease family protein -
INT76_RS01655 (INT76_01655) 335058..335810 - 753 WP_212571491.1 ABC transporter ATP-binding protein -
INT76_RS01660 (INT76_01660) 335869..336009 - 141 WP_212571493.1 hypothetical protein -
INT76_RS01665 (INT76_01665) 336342..337508 - 1167 WP_212571495.1 carbamoyl phosphate synthase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(10-76)

Antitoxin

Protein of unknown function DUF6290

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9977.49 Da        Isoelectric Point: 10.8277

>T199572 WP_212571486.1 NZ_CP073084:c332759-332502 [Streptococcus oriscaviae]
MKTYYKLVPTSRFIEQLKKLDKFTQKQITNYLSSHVTDNPRQHGKALTANRSGQWRYRIGNYRVITSIEDDKLIVTSLKM
RNGSV

Download         Length: 258 bp

>T199572 NZ_CP097411:2401476-2401793 [Klebsiella pneumoniae]
ATGTTGACTTTTATTGAACTACAAGGTTTCAGTAAGCGACGCCAGGTGCTGTTGCAGGATGATGAATTTCGGGCCTTTCA
GGAAATCCTTATAAACGATCCCGAGGCTGGGGACACAATTTCGGGAACCGGTGGTTTTCGTAAAATTCGCTGGAGTCGTC
CCGGGATGGGGAAGCGCGGCGGTGTACGAGTGATTTACTATAATGTAACGAAAAAGGGAAGAATTTACCTGGCGCTCATC
TATCCTAAAAATGAACAGGATGAGTTAAATCAGGAGCAAAAAAAGATGTTGAGACAAGTGGCTGATTTAATAAACTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9295.56 Da        Isoelectric Point: 3.7574

>AT199572 WP_212571488.1 NZ_CP073084:c332994-332743 [Streptococcus oriscaviae]
MAAITLKVSEQDKLFMQAMAKFEGVSLSELIRTKTLEALEDEYDARVADIALAEYEADLAKGIEPISWEEMLEDLGLTDE
DLL

Download         Length: 252 bp

>AT199572 NZ_CP097411:2401869-2402165 [Klebsiella pneumoniae]
ATGAAAGACGAATTGTTTGCCGATCTGCTGGCGAGTGCAGAAGAAATGGTCAGGATCGAGAAAGGTGAACAAATGCTGAT
GGAGCAGCACGTTCATACCTTCAGCGAAATTGACGTGAAAGCGATACGTGAAGCCACAGGTTTAAAACAGCAGGACTTTG
CAGCGGCCGTTGGCGTTAGCTACGAGTTGGTTAAAAGCTGGGAAACGAAACGACGTCACCCAACCGGTGCAGCCAGAAAG
CTGCTTTTATTGCTTCAGGGTAATCCATTGATTATCAACTTGTTGAAGGTTGTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References