199554

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1717077..1717641 Replicon chromosome
Accession NZ_CP073078
Organism Caulobacter sp. S6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KCG34_RS07560 Protein ID WP_211939770.1
Coordinates 1717360..1717641 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KCG34_RS07555 Protein ID WP_211939769.1
Coordinates 1717077..1717373 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KCG34_RS07530 (KCG34_07530) 1712613..1713077 - 465 WP_211939764.1 chemotaxis protein CheW -
KCG34_RS07535 (KCG34_07535) 1713122..1714621 - 1500 WP_211939765.1 methyl-accepting chemotaxis protein -
KCG34_RS07540 (KCG34_07540) 1714807..1715598 - 792 WP_211939766.1 competence/damage-inducible protein A -
KCG34_RS07545 (KCG34_07545) 1715658..1716395 + 738 WP_211939767.1 DNA/RNA nuclease SfsA -
KCG34_RS07550 (KCG34_07550) 1716473..1716940 + 468 WP_211939768.1 hypothetical protein -
KCG34_RS07555 (KCG34_07555) 1717077..1717373 + 297 WP_211939769.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
KCG34_RS07560 (KCG34_07560) 1717360..1717641 + 282 WP_211939770.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KCG34_RS07565 (KCG34_07565) 1717658..1718584 - 927 WP_211939771.1 hypothetical protein -
KCG34_RS07570 (KCG34_07570) 1718764..1719480 + 717 WP_211939772.1 TylF/MycF/NovP-related O-methyltransferase -
KCG34_RS07575 (KCG34_07575) 1719482..1720642 + 1161 WP_211939773.1 class I SAM-dependent methyltransferase -
KCG34_RS07580 (KCG34_07580) 1720775..1721596 + 822 WP_211939774.1 type I methionyl aminopeptidase -
KCG34_RS07585 (KCG34_07585) 1721668..1722273 + 606 WP_249138259.1 DNA repair protein RadC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-57)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10659.42 Da        Isoelectric Point: 10.6100

>T199554 WP_211939770.1 NZ_CP073078:1717360-1717641 [Caulobacter sp. S6]
VLALEWRQAARADLLAIVDFISDDNPEAAQRLKDQIEAKAAKLATRPKLYRHGRVPGTREMLVRPSYVVIYMENARAVTI
LRILHTARQWPQP

Download         Length: 282 bp

>T199554 NZ_CP097385:c1413271-1412987 [Klebsiella pneumoniae]
ATGACCTATGAACTGGAGTTTGATCCACGAGCCTGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGACCAGGCTGAGCGATTTACCGGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10796.36 Da        Isoelectric Point: 6.7260

>AT199554 WP_211939769.1 NZ_CP073078:1717077-1717373 [Caulobacter sp. S6]
MAQTTMLHVRVDNDLKADAAEKLASFGLTVSDAVRILLTRIVKEGGLPAGLAADPNAYDAWFRMKVHEALDDTRPAVDHR
QVMDEAQVLIDRKRRAGA

Download         Length: 297 bp

>AT199554 NZ_CP097385:c1413503-1413261 [Klebsiella pneumoniae]
ATGGCCACGCTCAATGTTCGACTGGACGATAAACTCAAAAAAGAGGCTTATGCCGTGCTGGAGAAACTCGATATGACACC
AACGGAGGCGGTACGCCTGCTGTTTCAATACATTGCGGAAAATGGCCGCATGCCGGTGAAAAGTATGACCATCAGTGATG
GCGAAGCGGCGTTATTACGCACCGTTCGCGAACGGCTGGAAAACCCACGGCCGGGGGTTAAGGTGAGTCTGGATGACCTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References