199525

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3346835..3347447 Replicon chromosome
Accession NZ_CP073017
Organism Synechocystis sp. PCC 6803

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KBZ93_RS15565 Protein ID WP_010874170.1
Coordinates 3347085..3347447 (+) Length 121 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KBZ93_RS15560 Protein ID WP_010874169.1
Coordinates 3346835..3347095 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBZ93_RS15545 (KBZ93_15550) 3343921..3344673 - 753 WP_223211306.1 hypothetical protein -
KBZ93_RS15550 (KBZ93_15555) 3344755..3345711 - 957 WP_010874167.1 quinolinate synthase NadA -
KBZ93_RS15555 (KBZ93_15560) 3345804..3346550 - 747 WP_010874168.1 cytochrome c biogenesis protein CcdA -
KBZ93_RS15560 (KBZ93_15565) 3346835..3347095 + 261 WP_010874169.1 hypothetical protein Antitoxin
KBZ93_RS15565 (KBZ93_15570) 3347085..3347447 + 363 WP_010874170.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KBZ93_RS15570 (KBZ93_15575) 3347584..3350190 + 2607 WP_010874171.1 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase -
KBZ93_RS15575 (KBZ93_15580) 3350420..3351247 + 828 WP_010874172.1 hypothetical protein -
KBZ93_RS15580 (KBZ93_15585) 3351576..3352097 + 522 WP_010874173.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(37-110)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13679.59 Da        Isoelectric Point: 8.2767

>T199525 WP_010874170.1 NZ_CP073017:3347085-3347447 [Synechocystis sp. PCC 6803]
MSNNLHLVNIDFTPEYRRSLKYLAKKYRNIRSDVQPIIEALQKGVISGDRLAGFGSDIYVYKLRIKNSNIQKGKSSGYRL
IYLLESENSILLLTIYSKAEQEDIAASDINSILGEYSIED

Download         Length: 363 bp

>T199525 NZ_CP097370:c4105857-4105480 [Escherichia coli]
ATGAAAACATTACCTGATACACACGTACGGAAGGTATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTACGGCCTTACGCTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCAGTGAACTTTCTCGTGGAAAAATACGCACTGGTACGTACCGACCTGCCGGGATTC
AGCGCCTGTACCCACTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCCGGGCAACAGGCCTGATGATCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGGAAGCATCCGGAGGCGAAACGATGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9909.29 Da        Isoelectric Point: 4.3705

>AT199525 WP_010874169.1 NZ_CP073017:3346835-3347095 [Synechocystis sp. PCC 6803]
MMRAFEVMATVKDSKQLLLDSDLHWNTSRVKVIILESDELASKGSEFDPDDTPVEEIKVSLRKALEEYKQGKRIPVENMW
EGIDVE

Download         Length: 261 bp

>AT199525 NZ_CP097370:c4106314-4105946 [Escherichia coli]
GTGTCAGACAAACTCTCCGGGATAACTCATCCCGATGACAATCACGACCGCCCCTGGTGGGGGCTTCCCTGCACAGTGAG
GCCCTGTTTTGGCGCTCGTCTGGTGCAAGAGGGTAACCGCCTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCGCT
TCAGCGACGCAGATGCATACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAATTAATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCGAAAGGACTGACCTGCGAAGCCGACACCCTCGGCAGTTG
TGGTTACGTTTATCTGGCTTTTTATCCAACATCCGAAACGAAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References