199522

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1933556..1934148 Replicon chromosome
Accession NZ_CP073017
Organism Synechocystis sp. PCC 6803

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KBZ93_RS09145 Protein ID WP_010872957.1
Coordinates 1933556..1933942 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KBZ93_RS09150 Protein ID WP_010872958.1
Coordinates 1933942..1934148 (-) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBZ93_RS09135 (KBZ93_09145) 1931227..1932399 + 1173 WP_010872955.1 sulfate adenylyltransferase -
KBZ93_RS09140 (KBZ93_09150) 1932442..1933506 + 1065 WP_010872956.1 glycosyltransferase -
KBZ93_RS09145 (KBZ93_09155) 1933556..1933942 - 387 WP_010872957.1 type II toxin-antitoxin system VapC family toxin Toxin
KBZ93_RS09150 (KBZ93_09160) 1933942..1934148 - 207 WP_010872958.1 DUF2281 domain-containing protein Antitoxin
KBZ93_RS09155 (KBZ93_09165) 1934395..1935618 - 1224 WP_010872959.1 geranylgeranyl reductase -
KBZ93_RS09160 (KBZ93_09170) 1936000..1937157 + 1158 WP_010872960.1 oxidoreductase -
KBZ93_RS09165 (KBZ93_09175) 1937174..1937485 + 312 WP_010872961.1 DUF433 domain-containing protein -
KBZ93_RS09170 (KBZ93_09180) 1937562..1938398 + 837 WP_010872962.1 LapA family protein -
KBZ93_RS09175 (KBZ93_09185) 1938517..1938870 + 354 WP_010872963.1 TMEM165/GDT1 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

VapC-like Sll0205 protein, PIN domain

(5-127)

Antitoxin

Domain of unknown function DUF2281

(7-67)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14814.14 Da        Isoelectric Point: 6.0713

>T199522 WP_010872957.1 NZ_CP073017:c1933942-1933556 [Synechocystis sp. PCC 6803]
MNSVLIDTHVFIWLAEDDSNLPVTTKDTLENMDNVFVSIASFWEISIKLKIGKLSLCGDFNSIEASFQRTRFKLLPITLK
DTIKLYNLPLHHKDPFDRILVSQSINHSLILVSRDQALDDYPIQRLWL

Download         Length: 387 bp

>T199522 NZ_CP097370:c3696300-3695380 [Escherichia coli]
ATGGATCTGCGTGATAGCTATGCCAGGCAGGTTAAACTGTTGATGGCCGCTCTGCCGCATGTGGCGAAGGAATCCTGTTT
CGCGTTGAAAGGCGGCACAGCAATCAATTTATTTGTGCAGGATTTCCCCCGTCTATCGGTGGATATCGATCTGGCGTATA
AGAGCTTTGCGGATCGCGATACCGATCTGGCGGCGATCAACGACGCTTTGAAGAGAATTACTGCATCGCTGAACGGCAGA
CCGGGGATCACCGCGATTCGGCAGGAAAATAAAGCGGATGAAAAGCGCATCATTGTGAATACCGCTGATGCAAAGATTAA
GATCGAGGTTAGCCCGGTCTGGCGCGGGCTGTTGTTGCCTCCGGCAGAAATGCCTGTGTGCGAACGTGTGGAAATGGAGT
ATGGCTTCACCACCATGAGTGTCGTCTCGCTGGCGGATCTTTATGGCGGTAAAATATGTGCTGCGCTTGATCGTCAGCAT
CCGCGCGATCTGTTTGATGTGTTGAATATGCTGGGGAGACCGGGCCTGACGCGCGAAATTTTTGACGGTTTTCTTTGTTA
TCTGGCAGGCCATCCCCGTCCCATTGCCGAGTTGCTGGCTTCAAACTGGGATACAGATCGGATTGCCACGTTATACGCTC
AGGAATTTTCGGGGATGACTCAGCAGGAAACGTCGCTGGAATCGCTTCTGTCAGTAACGACTTTGCTGCCGCAGGCGTTG
AAGTCACATTTTACGGATCTGGATCGCGAGTTCTTGCTCAGTTTTAAGCAAAACAGCCCTGACTGGTCGCGGTATCGCTA
TCCTGAAATTCAGCATCTTCCGGCTATTCGCTGGAAGCAACGCAATCTGGCGATGCTTAAAGATAAAAATCCGGCGAAGT
ATGTGGCGGCGGTGAATAAGCTAGAGAGGGTGCTGGAGTAA

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7699.84 Da        Isoelectric Point: 3.8804

>AT199522 WP_010872958.1 NZ_CP073017:c1934148-1933942 [Synechocystis sp. PCC 6803]
MTTEAALLNIAENLPDDLKIELLHYAEYLMNKSLNAPQKPLAGSMKGTFILPLPEDFDAPLEEFEEYM

Download         Length: 207 bp

>AT199522 NZ_CP097370:c3697069-3696287 [Escherichia coli]
TTGCCAAACTATCTAAACTGGTTGATGCAAAACACGCTACCCGGTCAGGTGCTGCTCCAGTCATGGCTTACCCGCAATGG
CGTAGATCGTAAGCTTTCTTATCTCTATGTTCAGAATGGCTGGCTCAGGCGCATCGCTCACGGTGTGTACTGCCGGACGG
GCCGTGAGCCGGATTGGGTAGACGCGGTTTACTGCCTTCAAACACAGTGGGAAAAGCCTGTTCGGGTGGCGGGGCTAACC
AGCCTTGCGCTTCAGGGCCATGCGCACTATACCGAACCGGGTAAGCCGCAGGTCTGGCTCGCGCTTCCGGCTTACGTCAA
ACTGCCGGGATGGTTTGCTGCCTTCGAACAATCAGCAACATTTATCACGCTGTATACATCGGGCCTTACCGTTGATGTCT
CGTCATTTACTACGGAACTGAAAATTGGCGACCGGCAGTTAGCAGGCAGTGCACCGGAACTGGCCGCGTATGAGATCGCC
TGCGGCGTTCCTTCGTTGATCTCGTTCGAACATGCCGATGCTCTGTTTCAGGGGGGGAATCTTCTCAGCCCACGCAAATT
GCAGGCACTGCTTCGCGCCAGTCATTCGATTAAAACCAACCGGGTGATGCTTTACCTTGCCCGGCGTAATGGACACCCTT
ATTTTCAGTATCTTGATCAAAGCGGTATAGAAACAGGTACGGGAAAGCGGCAAATCATACCTGGTGGCTGGCTGGAGCCG
GATTATCAAATTACTGTTCCCCGCACATTTAAACCGGAAGGAGTCGAAGATGGATCTGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References