Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1660157..1660799 Replicon chromosome
Accession NZ_CP073017
Organism Synechocystis sp. PCC 6803

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KBZ93_RS07825 Protein ID WP_010872706.1
Coordinates 1660365..1660799 (+) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KBZ93_RS07820 Protein ID WP_010872705.1
Coordinates 1660157..1660375 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBZ93_RS07805 (KBZ93_07810) 1655377..1655796 - 420 WP_231848060.1 heterocyst frequency control protein PatD -
KBZ93_RS07810 (KBZ93_07815) 1656131..1658413 + 2283 WP_010872703.1 RelA/SpoT family protein -
KBZ93_RS07815 (KBZ93_07820) 1658599..1659876 - 1278 WP_010872704.1 adenosylhomocysteinase -
KBZ93_RS07820 (KBZ93_07825) 1660157..1660375 + 219 WP_010872705.1 hypothetical protein Antitoxin
KBZ93_RS07825 (KBZ93_07830) 1660365..1660799 + 435 WP_010872706.1 putative toxin-antitoxin system toxin component, PIN family Toxin
KBZ93_RS07830 (KBZ93_07835) 1660827..1661711 - 885 WP_010872707.1 transglutaminase family protein -
KBZ93_RS07835 (KBZ93_07840) 1661810..1662373 - 564 WP_010872708.1 Uma2 family endonuclease -
KBZ93_RS07840 (KBZ93_07845) 1662394..1663590 - 1197 WP_041425818.1 glycosyltransferase family 1 protein -
KBZ93_RS07845 (KBZ93_07850) 1663642..1664721 - 1080 WP_230401109.1 hybrid sensor histidine kinase/response regulator -
KBZ93_RS18570 1664695..1664838 + 144 WP_223211387.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 16459.94 Da        Isoelectric Point: 4.4099

>T199521 WP_010872706.1 NZ_CP073017:1660365-1660799 [Synechocystis sp. PCC 6803]
MNNEVIRVVIDTNIWISFLIGKTLQGLNQAIIDNQVVILFSDTLFTELMEVLHHPKFKKYFSGTAIQNLIALLNEKVELV
EVNLHFDSYRDKKDNFLLDLAVSGNANYLVTGDSDLLTLNPFDNVEIISYQHFQAIILAMMDNQ

Download         Length: 435 bp

>T199521 NZ_CP097370:3513585-3513803 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGTCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCTGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8400.43 Da        Isoelectric Point: 4.2583

>AT199521 WP_010872705.1 NZ_CP073017:1660157-1660375 [Synechocystis sp. PCC 6803]
MHSLSSLEFPELKSVIAQCNLEEKLELLELLEKDTFGTRFNKFLNSVKTDELTLEDITQEVESVRQANYHEQ

Download         Length: 219 bp

>AT199521 NZ_CP097370:3513185-3513559 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References