199520

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 545118..545677 Replicon chromosome
Accession NZ_CP073017
Organism Synechocystis sp. PCC 6803

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KBZ93_RS02535 Protein ID WP_010871694.1
Coordinates 545339..545677 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KBZ93_RS02530 Protein ID WP_010871693.1
Coordinates 545118..545342 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBZ93_RS02510 (KBZ93_02520) 540952..542154 + 1203 WP_010871689.1 class I SAM-dependent methyltransferase -
KBZ93_RS02515 (KBZ93_02525) 542194..542685 - 492 WP_010871690.1 hypothetical protein -
KBZ93_RS02520 (KBZ93_02530) 542892..543431 + 540 WP_010871691.1 TerD family protein -
KBZ93_RS02525 (KBZ93_02535) 543557..544960 - 1404 WP_010871692.1 glutamate decarboxylase -
KBZ93_RS02530 (KBZ93_02540) 545118..545342 + 225 WP_010871693.1 DUF433 domain-containing protein Antitoxin
KBZ93_RS02535 (KBZ93_02545) 545339..545677 + 339 WP_010871694.1 DUF5615 family PIN-like protein Toxin
KBZ93_RS02540 (KBZ93_02550) 545680..546645 - 966 WP_010871695.1 carbon-nitrogen hydrolase family protein -
KBZ93_RS02545 (KBZ93_02555) 546642..547454 - 813 WP_014407074.1 urease accessory protein UreD -
KBZ93_RS02550 (KBZ93_02560) 547514..547963 - 450 WP_010871697.1 photosystem II protein PsbQ -
KBZ93_RS02555 (KBZ93_02565) 548325..549221 + 897 WP_010871698.1 prohibitin family protein -
KBZ93_RS02560 (KBZ93_02570) 549218..549790 - 573 WP_010871699.1 gamma carbonic anhydrase family protein -
KBZ93_RS02565 (KBZ93_02575) 550083..550418 + 336 WP_010871700.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12464.32 Da        Isoelectric Point: 4.2931

>T199520 WP_010871694.1 NZ_CP073017:545339-545677 [Synechocystis sp. PCC 6803]
MNIWVDAQLPPTLADWLSSNFDLEASALRDLGLRDARDIEIFDAARVANSVIMTKDSDFVDLVCRLGIPPQIIWLTCGNV
TNRNLRRILSSTLPQALEKLQAGEIIIEISNS

Download         Length: 339 bp

>T199520 NZ_CP097370:c3484631-3484329 [Escherichia coli]
ATGGCTCAAAAGAAAAATATAAGGAGTTTTCGTGATGCCTGGTTGGCTGATTTTTTTGTCCATTCAACGCCACATCGAAA
GATCCCTGCTGAAATCCATACCACGTTATCACGAAAGTTGGACATCATTAATGCTGCCACTTCTCATCGGGATTTACGCT
CCCCTCCGGGGAACCGATACGAAGAGTTATCCGGGAAATTACAGGAATACTCCTCCATTAGAGTGAATAAACAGTACCGA
CTGATTTTTAAATGGGTTAATGGCAAGGCCGAAGAATTGTTTTTAGACCCACACAACTACTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8232.51 Da        Isoelectric Point: 4.6320

>AT199520 WP_010871693.1 NZ_CP073017:545118-545342 [Synechocystis sp. PCC 6803]
MNSLLSRITQTPGQCGGRPCIRGMRIRVSDILEMLAENVSTSEILEDFPDLEMADIQACLVFAARRTDFSRLTA

Download         Length: 225 bp

>AT199520 NZ_CP097370:c3484293-3483952 [Escherichia coli]
ATGAAACAGGCAACAAGAAAACCGACGACACCCGGAGATATTCTTCTCTATGAATATCTGGAACCGCTCGATTTGAAAAT
CAATGAGTTAGCAGAGTTGCTGCATGTTCATCGTAATAGCGTCAGTGCACTGATCAATAACAATCGTAAACTCACCACTG
AGATGGCATTCCGTCTGGCGAAAGTTTTTGATACCACAGTCGATTTTTGGCTAAACCTCCAGGCGGCAGTTGATCTTTGG
GAAGTTGAAAACAACATGCGTACCCAGGAAGAATTGGGACGGATTGAAACAGTGGCTGAATATTTGGCACGCCGTGAAGA
GCGTGCAAAAAAGGTCGCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References