Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2070437..2070582 Replicon chromosome
Accession NZ_CP072996
Organism Klebsiella pneumoniae strain KP1878

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2070473..2070575 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2070437..2070582 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KA532_RS10175 (KA532_10175) 2065567..2067627 + 2061 WP_004151449.1 oligopeptidase B -
KA532_RS10180 (KA532_10180) 2067631..2068290 - 660 WP_002911407.1 exodeoxyribonuclease X -
KA532_RS10185 (KA532_10185) 2068369..2068599 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KA532_RS10190 (KA532_10190) 2068712..2069086 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KA532_RS10195 (KA532_10195) 2069090..2069959 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
KA532_RS10200 (KA532_10200) 2069976..2070314 + 339 WP_002911404.1 YebY family protein -
- 2070437..2070582 - 146 - - Antitoxin
- 2070473..2070575 + 103 - - Toxin
KA532_RS10205 (KA532_10205) 2070950..2071093 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KA532_RS10210 (KA532_10210) 2071198..2072166 - 969 WP_004151446.1 VirK/YbjX family protein -
KA532_RS10215 (KA532_10215) 2072323..2072976 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KA532_RS10220 (KA532_10220) 2072973..2073164 - 192 WP_002911395.1 YebW family protein -
KA532_RS10225 (KA532_10225) 2073262..2073501 - 240 WP_002911393.1 YebV family protein -
KA532_RS10230 (KA532_10230) 2073617..2075050 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T199437 NZ_CP072996:2070473-2070575 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT199437 NZ_CP072996:c2070582-2070437 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References