199431

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 3932436..3932821 Replicon chromosome
Accession NZ_CP072990
Organism Xanthomonas translucens pv. translucens strain CIX95

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag KBV71_RS17110 Protein ID WP_003469322.1
Coordinates 3932436..3932570 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag KBV71_RS17115 Protein ID WP_003469323.1
Coordinates 3932669..3932821 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBV71_RS17095 (KBV71_16960) 3928886..3929809 - 924 WP_242786321.1 MBL fold metallo-hydrolase -
KBV71_RS17100 (KBV71_16965) 3929865..3931265 - 1401 WP_060744654.1 tryptophan--tRNA ligase -
KBV71_RS17105 (KBV71_16970) 3931376..3932227 + 852 WP_003476578.1 hypothetical protein -
KBV71_RS17110 (KBV71_16975) 3932436..3932570 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
KBV71_RS17115 (KBV71_16980) 3932669..3932821 - 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
KBV71_RS17120 (KBV71_16985) 3932965..3933888 - 924 WP_003476579.1 arginase -
KBV71_RS17130 (KBV71_16995) 3934276..3935091 - 816 WP_242786322.1 SPOR domain-containing protein -
KBV71_RS17135 (KBV71_17000) 3935101..3935841 - 741 WP_004427869.1 type III pantothenate kinase -
KBV71_RS17140 (KBV71_17005) 3935838..3936833 - 996 WP_231893612.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
KBV71_RS17145 (KBV71_17010) 3936971..3937243 + 273 WP_003476582.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-39)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T199431 WP_003469322.1 NZ_CP072990:c3932570-3932436 [Xanthomonas translucens pv. translucens]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T199431 NZ_CP097340:c256789-256457 [Mannheimia haemolytica]
ATGAAACGTGGCGATATTTACTGGCTCGATCTTGATCCAACCTTAGGACACGAACAATCAGGCTTCCGCCCCGTTGTAAT
TGTTTCCGCAACTGCATTTAATCTAGCCAGTAAACTGCCTGTGGTTGTGCCGATTACTAACGGTGGAGCTTTTGCTGAAA
GACTGGGCTTTGCCGTTTCATTAAAAGATGCCGGCTTAAAAACAACAGGGATTATTCGATGCGATCAACCTCGCACAGTC
GATATTGCACAACGCCATGGAAAATTTATCGAAGCCTTACCCGAAAGCCTACTTGATGAAATTATGGCAAGGGTTTCAGT
GATTTTTGAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT199431 WP_003469323.1 NZ_CP072990:c3932821-3932669 [Xanthomonas translucens pv. translucens]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT199431 NZ_CP097340:c257046-256786 [Mannheimia haemolytica]
ATGCCAACAATCGCATTACGTCAGGTCGGTGGCTCGGTTGCAATGGTGATTCCGCCTGCTTTTTTAGAGGCACTCAAGCT
CTCCGTCGGTAGCAAAGTGGATTTGTCTTTAAACGACAACCAACTCGTGATTAATCCTGCCCGCCCAAAAGTGAAATACA
GCTTAGAGGAATTATTAAGACAATCCGATTTTGAGGCAGCAAGGAATGAAGAAAGCCAATCGTGGTTATCCGAGCCGGCA
ATAGGAAAAGAAATTTTATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5


Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References