Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 3066905..3067410 Replicon chromosome
Accession NZ_CP072990
Organism Xanthomonas translucens pv. translucens strain CIX95

Toxin (Protein)


Gene name relE Uniprot ID A0A1C3TRG2
Locus tag KBV71_RS13090 Protein ID WP_003479798.1
Coordinates 3067153..3067410 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A1C3TRJ9
Locus tag KBV71_RS13085 Protein ID WP_003468816.1
Coordinates 3066905..3067156 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBV71_RS13060 (KBV71_12945) 3061976..3063211 + 1236 WP_065899003.1 citrate synthase family protein -
KBV71_RS13065 3063913..3064932 + 1020 WP_229017866.1 hypothetical protein -
KBV71_RS13070 (KBV71_12955) 3064968..3065411 - 444 WP_003479801.1 nuclear transport factor 2 family protein -
KBV71_RS13075 (KBV71_12960) 3065533..3066255 + 723 WP_003479800.1 helix-turn-helix transcriptional regulator -
KBV71_RS13080 (KBV71_12965) 3066252..3066796 - 545 Protein_2584 endonuclease -
KBV71_RS13085 (KBV71_12970) 3066905..3067156 + 252 WP_003468816.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KBV71_RS13090 (KBV71_12975) 3067153..3067410 + 258 WP_003479798.1 Txe/YoeB family addiction module toxin Toxin
KBV71_RS13100 (KBV71_12985) 3068045..3068398 - 354 WP_003479797.1 PilZ domain-containing protein -
KBV71_RS13105 (KBV71_12990) 3068395..3069372 - 978 WP_003479796.1 DNA polymerase III subunit delta' -
KBV71_RS13110 (KBV71_12995) 3069369..3070037 - 669 WP_003479795.1 dTMP kinase -
KBV71_RS13115 (KBV71_13000) 3070034..3071101 - 1068 WP_242786205.1 endolytic transglycosylase MltG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10156.61 Da        Isoelectric Point: 9.7381

>T199430 WP_003479798.1 NZ_CP072990:3067153-3067410 [Xanthomonas translucens pv. translucens]
VTLQFSDNAWEDDLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPERLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYA

Download         Length: 258 bp

>T199430 NZ_CP097340:c75794-75366 [Mannheimia haemolytica]
ATGTATCGCTACCTTTTTGATACCAATATAGTTTCCGAGCTTTATAAGTTAAGAAATGACAAGATGGATGTCAATGTTCG
CCAGTGGCTGAGAGGGGTTAATCCTAGCCAGACCAATATCAGCTGTATTACGTTATCTGAAATCAAAACAGGTATTTTGC
TGAAAGCCCGCAAAGACAAAGAACAATCAGACCGATTAAATGATTGGTTTGAAAATAATGTATTAAAGGCTTATCAAACA
AAAGCGTTTGTGGTGAATAACGACATTGCTCTATTGGCATCAGAGTACCATATTCCCAATAAAATGGATTTAAATGATGC
TTATATTGCGGCAACCGCCAAATACCACAATCTGATTTTAGTCACCCGCAACACCAAAGATTTTATCCGTTGTGATGTGC
GTTTATTTAACCCATTTGAAACCGCATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9281.56 Da        Isoelectric Point: 5.1186

>AT199430 WP_003468816.1 NZ_CP072990:3066905-3067156 [Xanthomonas translucens pv. translucens]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Download         Length: 252 bp

>AT199430 NZ_CP097340:c76081-75794 [Mannheimia haemolytica]
ATGGCAATAACCATTACTTCCAGAGAATTTAATCAAAATGCCAGCAAAGTGTTAAAAATGGCAGAAAAAGAGCCGGTTTT
TATTACCAAATGGGGCAAAATCGTCAATGTGGTGTCTAGTTATATGGATTATCAGCAGAAAAAGCCTAGCGAGCCAAGCT
TTGAAGAGCTATTCGCCTCTTCCGAAAATGAGGATGTGAGCGATGAATTTTGGCAAGAGTTTGAACAAACATTGGTTGAA
ATCCGCAAAAGCAATAAACCAAGACCTGTTGATTTTGGAGATGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1C3TRG2

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TRJ9

References