Detailed information of TA system TA199429

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/-
• Location: 50239..51805
• Replicon: chromosome
• Accession: NZ_CP072990
• Organism: Xanthomonas translucens pv. translucens strain CIX95

Toxin (Protein)

• Gene name: avrRxo1
• Uniprot ID: -
• Locus tag: KBV71_RS00215
• Protein ID: WP_003480647.1
• Coordinates: 50549..51805 (-)
• Length: 419 a.a.

Antitoxin (Protein)

• Gene name: arc1
• Uniprot ID: -
• Locus tag: KBV71_RS00210
• Protein ID: WP_003480646.1
• Coordinates: 50239..50535 (-)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KBV71_RS00180 (KBV71_00180)	46101..47015	-	915	WP_003465336.1	YihY/virulence factor BrkB family protein	-
KBV71_RS00185 (KBV71_00185)	47150..47599	-	450	WP_003480639.1	GatB/YqeY domain-containing protein	-
KBV71_RS00190 (KBV71_00190)	47879..48094	-	216	WP_003465342.1	30S ribosomal protein S21	-
KBV71_RS00195 (KBV71_00195)	48216..49364	+	1149	WP_058360827.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	-
KBV71_RS00200 (KBV71_00200)	49357..49710	+	354	WP_003480645.1	dihydroneopterin aldolase	-
KBV71_RS00205 (KBV71_00205)	49791..50066	+	276	WP_128809232.1	hypothetical protein	-
KBV71_RS00210 (KBV71_00210)	50239..50535	-	297	WP_003480646.1	hypothetical protein	Antitoxin
KBV71_RS00215 (KBV71_00215)	50549..51805	-	1257	WP_003480647.1	XopAJ/AvrRxo1 family type III secretion system effector zeta toxin	Toxin
KBV71_RS00220 (KBV71_00220)	52105..53553	+	1449	WP_003480648.1	circularly permuted type 2 ATP-grasp protein	-
KBV71_RS00225 (KBV71_00225)	53553..54494	+	942	WP_003465367.1	alpha-E domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (148-285)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 419 a.a.
• Molecular weight: 45042.67 Da
• Isoelectric Point: 6.6145

>T199429 WP_003480647.1 NZ_CP072990:c51805-50549 [Xanthomonas translucens pv. translucens]
MKGKISNACKPDITPILVDGLASTATQGAADDSASRLPQQALLDGLQERPQALKKSNSADWSARTLPQWAPGPGTSSKAL
LIQSPPHPTSSDEMFGLGELPAPGKARWEYLTKTENWHPERQELHSRLLSQARTASLRLAESIESDGYPPTLFALRGNTA
TGKTRIATKTIPVLANALKKSSGGGCINPDIFKRSLAESQGEAMKLSSAQVHAESCVLADRLENELRSQRTTSGAMASIL
VDKRLANTHEVDSYVSLAKETGRKVELCDIDAPLERSLMGVLQRSPGGDDPRPPYVAVANGFSTVRSNRLDVIDRFLSNP
TLGSYRLFGTNEKGEKVMVASVADGELSIHDPQLYESITAPEDFNSGDKGEQVIDTALIDRLSNSIDDPKRATDARAALE
KYKGMTWSNALAAHSSLI

Nucleotide

• Length: 1257 bp

>T199429 NZ_CP097339:c2316576-2316148 [Mannheimia haemolytica]
ATGTATCGCTACCTTTTTGATACCAATATAGTTTCCGAGCTTTATAAGTTAAGAAATGACAAGATGGATGTCAATGTTCG
CCAGTGGCTGAGAGGGGTTAATCCTAGCCAGACCAATATCAGCTGTATTACGTTATCTGAAATCAAAACAGGTATTTTGC
TGAAAGCCCGCAAAGACAAAGAACAATCAGACCGATTAAATGATTGGTTTGAAAATAATGTATTAAAGGCTTATCAAACA
AAAGCGTTTGTGGTGAATAACGACATTGCTCTATTGGCATCAGAGTACCATATTCCCAATAAAATGGATTTAAATGATGC
TTATATTGCGGCAACCGCCAAATACCACAATCTGATTTTAGTCACCCGCAACACCAAAGATTTTATCCGTTGTGATGTGC
GTTTATTTAACCCATTTGAAACCGCATAA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 11088.54 Da
• Isoelectric Point: 7.3576

>AT199429 WP_003480646.1 NZ_CP072990:c50535-50239 [Xanthomonas translucens pv. translucens]
MTHLKGADALALHKKLKERNASLRSAELDSAKALAHESGKERFNLEKLESICDTTQAGRITDPNDRQAIYEQMYYVEHPK
VSTLQEFARIVVTISSWS

Nucleotide

• Length: 297 bp

>AT199429 NZ_CP097339:c2316863-2316576 [Mannheimia haemolytica]
ATGGCAATAACCATTACTTCCAGAGAATTTAATCAAAATGCCAGCAAAGTGTTAAAAATGGCAGAAAAAGAGCCGGTTTT
TATTACCAAATGGGGCAAAATCGTCAATGTGGTGTCTAGTTATATGGATTATCAGCAGAAAAAGCCTAGCGAGCCAAGCT
TTGAAGAGCTATTCGCCTCTTCCGAAAATGAGGATGTGAGCGATGAATTTTGGCAAGAGTTTGAACAAACATTGGTTGAA
ATCCGCAAAAGCAATAAACCAAGACCTGTTGATTTTGGAGATGAGTAA