Detailed information of TA system TA199428

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/-
• Location: 4109963..4111529
• Replicon: chromosome
• Accession: NZ_CP072988
• Organism: Xanthomonas translucens pv. translucens strain CIX43

Toxin (Protein)

• Gene name: avrRxo1
• Uniprot ID: -
• Locus tag: KBQ49_RS17855
• Protein ID: WP_003480647.1
• Coordinates: 4110273..4111529 (-)
• Length: 419 a.a.

Antitoxin (Protein)

• Gene name: arc1
• Uniprot ID: -
• Locus tag: KBQ49_RS17850
• Protein ID: WP_003480646.1
• Coordinates: 4109963..4110259 (-)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KBQ49_RS17820 (KBQ49_17730)	4105825..4106739	-	915	WP_003465336.1	YihY/virulence factor BrkB family protein	-
KBQ49_RS17825 (KBQ49_17735)	4106874..4107323	-	450	WP_003480639.1	GatB/YqeY domain-containing protein	-
KBQ49_RS17830 (KBQ49_17740)	4107603..4107818	-	216	WP_003465342.1	30S ribosomal protein S21	-
KBQ49_RS17835 (KBQ49_17745)	4107940..4109088	+	1149	WP_058360827.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	-
KBQ49_RS17840 (KBQ49_17750)	4109081..4109434	+	354	WP_003480645.1	dihydroneopterin aldolase	-
KBQ49_RS17845 (KBQ49_17755)	4109515..4109790	+	276	WP_128809232.1	hypothetical protein	-
KBQ49_RS17850 (KBQ49_17760)	4109963..4110259	-	297	WP_003480646.1	hypothetical protein	Antitoxin
KBQ49_RS17855 (KBQ49_17765)	4110273..4111529	-	1257	WP_003480647.1	XopAJ/AvrRxo1 family type III secretion system effector zeta toxin	Toxin
KBQ49_RS17860 (KBQ49_17770)	4111829..4113277	+	1449	WP_003480648.1	circularly permuted type 2 ATP-grasp protein	-
KBQ49_RS17865 (KBQ49_17775)	4113277..4114218	+	942	WP_003465367.1	alpha-E domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (148-285)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 419 a.a.
• Molecular weight: 45042.67 Da
• Isoelectric Point: 6.6145

>T199428 WP_003480647.1 NZ_CP072988:c4111529-4110273 [Xanthomonas translucens pv. translucens]
MKGKISNACKPDITPILVDGLASTATQGAADDSASRLPQQALLDGLQERPQALKKSNSADWSARTLPQWAPGPGTSSKAL
LIQSPPHPTSSDEMFGLGELPAPGKARWEYLTKTENWHPERQELHSRLLSQARTASLRLAESIESDGYPPTLFALRGNTA
TGKTRIATKTIPVLANALKKSSGGGCINPDIFKRSLAESQGEAMKLSSAQVHAESCVLADRLENELRSQRTTSGAMASIL
VDKRLANTHEVDSYVSLAKETGRKVELCDIDAPLERSLMGVLQRSPGGDDPRPPYVAVANGFSTVRSNRLDVIDRFLSNP
TLGSYRLFGTNEKGEKVMVASVADGELSIHDPQLYESITAPEDFNSGDKGEQVIDTALIDRLSNSIDDPKRATDARAALE
KYKGMTWSNALAAHSSLI

Nucleotide

• Length: 1257 bp

>T199428 NZ_CP097339:c1760796-1760407 [Mannheimia haemolytica]
ATGTATATGTTAGATACGAATACTGTAAGCTATTTTTTTCGTGGAAATGCAAATGTGGTGGCGAAATTGAAGTCCATTAA
TCCTGAGAGGCTTTGTATTTCATCTGTAACTGCTGCTGAATTGGTTTATGGTGTGGCGAAAAGAAATAATGGGCAGCTTT
CTCAATTTTTAGATTATTTTTTATCGAGTGTAAAGGTTTTAGATTGGAATTATCGTTGTGCTGAACTTTATGGAAAGTTA
CGGGCAGAGATGGAGAAAAATGGCAAAGTAATGGGCGTGCAGGATCAAATGATTGCTAGTCACGCTCTTGCTGAAGAGTG
TATTTTAGTTTCTAGTGATCAGGCATTTAAAATGGTACCTGATCTGAAATTGGAGAATTGGTTACACTAA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 11088.54 Da
• Isoelectric Point: 7.3576

>AT199428 WP_003480646.1 NZ_CP072988:c4110259-4109963 [Xanthomonas translucens pv. translucens]
MTHLKGADALALHKKLKERNASLRSAELDSAKALAHESGKERFNLEKLESICDTTQAGRITDPNDRQAIYEQMYYVEHPK
VSTLQEFARIVVTISSWS

Nucleotide

• Length: 297 bp

>AT199428 NZ_CP097339:c1761057-1760797 [Mannheimia haemolytica]
ATGGAAAAAATTGCGAGATTATTCCGTAACGGGCGGAACCAAGCAGTGCGTTTACCGGTTGAATTTGAGTTTGATGCAGA
GCAAGTCTATGTTTCTAAAAAAGAAAATGGCGATATTTTATTATCATTGAGATCGAGAAATACCGAGCATTGGCAACGAT
TGTTTGAGCTATTGCCTGCTGTTGTATGTGATGAAACATTTTTAGATACAAAAGAGAGAAACCAATCCTTTGAGCAACGG
GATCCTTTTGAGGTAGCTTAA