Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 2344168..2344673 Replicon chromosome
Accession NZ_CP072988
Organism Xanthomonas translucens pv. translucens strain CIX43

Toxin (Protein)


Gene name relE Uniprot ID A0A1C3TRG2
Locus tag KBQ49_RS10105 Protein ID WP_003479798.1
Coordinates 2344416..2344673 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A1C3TRJ9
Locus tag KBQ49_RS10100 Protein ID WP_003468816.1
Coordinates 2344168..2344419 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBQ49_RS10075 (KBQ49_10030) 2339239..2340474 + 1236 WP_065899003.1 citrate synthase family protein -
KBQ49_RS10080 2341176..2342195 + 1020 WP_229017866.1 hypothetical protein -
KBQ49_RS10085 (KBQ49_10040) 2342231..2342674 - 444 WP_003479801.1 nuclear transport factor 2 family protein -
KBQ49_RS10090 (KBQ49_10045) 2342796..2343518 + 723 WP_003479800.1 helix-turn-helix transcriptional regulator -
KBQ49_RS10095 (KBQ49_10050) 2343515..2344059 - 545 Protein_1996 endonuclease -
KBQ49_RS10100 (KBQ49_10055) 2344168..2344419 + 252 WP_003468816.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KBQ49_RS10105 (KBQ49_10060) 2344416..2344673 + 258 WP_003479798.1 Txe/YoeB family addiction module toxin Toxin
KBQ49_RS10115 (KBQ49_10070) 2345308..2345661 - 354 WP_003479797.1 PilZ domain-containing protein -
KBQ49_RS10120 (KBQ49_10075) 2345658..2346635 - 978 WP_003479796.1 DNA polymerase III subunit delta' -
KBQ49_RS10125 (KBQ49_10080) 2346632..2347300 - 669 WP_003479795.1 dTMP kinase -
KBQ49_RS10130 (KBQ49_10085) 2347297..2348364 - 1068 WP_172837969.1 endolytic transglycosylase MltG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10156.61 Da        Isoelectric Point: 9.7381

>T199426 WP_003479798.1 NZ_CP072988:2344416-2344673 [Xanthomonas translucens pv. translucens]
VTLQFSDNAWEDDLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPERLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYA

Download         Length: 258 bp

>T199426 NZ_CP097339:c800041-799859 [Mannheimia haemolytica]
ATGAAATACAGCGAGTTCCTGAGGTACTTACTTGCTCAAGGTTGCGAAATTGAAAACCATAGGCGAGGCAGTCATCGAAA
GGTAACACTAAACGGAAAACAATCGGTTTTTCCTTATCACGGGAGCAAAGAGATTGGTACAGGTTTAGTAAATAAGATTA
AGAAAGACTTAGATCTTAAATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9281.56 Da        Isoelectric Point: 5.1186

>AT199426 WP_003468816.1 NZ_CP072988:2344168-2344419 [Xanthomonas translucens pv. translucens]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Download         Length: 252 bp

>AT199426 NZ_CP097339:c799820-799401 [Mannheimia haemolytica]
ATGTTACGCTACCCAGTTGAAATTACCCCTGATGATAACGGCACATATCTTGTGACTTGCCCTGATATTCCTGAAATGGC
AAGCGTAGGTGAGGACTTAGAAGAAGCCCTATTAGAAGCACAAGATGGCTTAGCCACAGCCCTTGAATTCTATTTTGATG
ATAGACGAGAAATACCAATGCCAAGCCCAATTAAAGAGGGACAACATACGGTTAATCTTACCGTGCTGCAATCAATGAAA
GTATTTCTCTTAAATGAAATGATTAAACAAGGTGTACGCAAAGCAGAAATGGCAAGACGATTAGATGTACACTTACCACA
GATAGATCGCCTATTAGATTTTAATCATTCCACAAAAGTAGAATTTGTTGAGAAAGCCTATGGTAAGCTAAATCAACACT
TTACTATTCTCCCTCACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1C3TRG2

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TRJ9

References