Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/YoeB-YefM |
Location | 2344168..2344673 | Replicon | chromosome |
Accession | NZ_CP072988 | ||
Organism | Xanthomonas translucens pv. translucens strain CIX43 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A1C3TRG2 |
Locus tag | KBQ49_RS10105 | Protein ID | WP_003479798.1 |
Coordinates | 2344416..2344673 (+) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | relE | Uniprot ID | A0A1C3TRJ9 |
Locus tag | KBQ49_RS10100 | Protein ID | WP_003468816.1 |
Coordinates | 2344168..2344419 (+) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KBQ49_RS10075 (KBQ49_10030) | 2339239..2340474 | + | 1236 | WP_065899003.1 | citrate synthase family protein | - |
KBQ49_RS10080 | 2341176..2342195 | + | 1020 | WP_229017866.1 | hypothetical protein | - |
KBQ49_RS10085 (KBQ49_10040) | 2342231..2342674 | - | 444 | WP_003479801.1 | nuclear transport factor 2 family protein | - |
KBQ49_RS10090 (KBQ49_10045) | 2342796..2343518 | + | 723 | WP_003479800.1 | helix-turn-helix transcriptional regulator | - |
KBQ49_RS10095 (KBQ49_10050) | 2343515..2344059 | - | 545 | Protein_1996 | endonuclease | - |
KBQ49_RS10100 (KBQ49_10055) | 2344168..2344419 | + | 252 | WP_003468816.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
KBQ49_RS10105 (KBQ49_10060) | 2344416..2344673 | + | 258 | WP_003479798.1 | Txe/YoeB family addiction module toxin | Toxin |
KBQ49_RS10115 (KBQ49_10070) | 2345308..2345661 | - | 354 | WP_003479797.1 | PilZ domain-containing protein | - |
KBQ49_RS10120 (KBQ49_10075) | 2345658..2346635 | - | 978 | WP_003479796.1 | DNA polymerase III subunit delta' | - |
KBQ49_RS10125 (KBQ49_10080) | 2346632..2347300 | - | 669 | WP_003479795.1 | dTMP kinase | - |
KBQ49_RS10130 (KBQ49_10085) | 2347297..2348364 | - | 1068 | WP_172837969.1 | endolytic transglycosylase MltG | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 10156.61 Da Isoelectric Point: 9.7381
>T199426 WP_003479798.1 NZ_CP072988:2344416-2344673 [Xanthomonas translucens pv. translucens]
VTLQFSDNAWEDDLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPERLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYA
VTLQFSDNAWEDDLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPERLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYA
Download Length: 258 bp
>T199426 NZ_CP097339:c800041-799859 [Mannheimia haemolytica]
ATGAAATACAGCGAGTTCCTGAGGTACTTACTTGCTCAAGGTTGCGAAATTGAAAACCATAGGCGAGGCAGTCATCGAAA
GGTAACACTAAACGGAAAACAATCGGTTTTTCCTTATCACGGGAGCAAAGAGATTGGTACAGGTTTAGTAAATAAGATTA
AGAAAGACTTAGATCTTAAATAA
ATGAAATACAGCGAGTTCCTGAGGTACTTACTTGCTCAAGGTTGCGAAATTGAAAACCATAGGCGAGGCAGTCATCGAAA
GGTAACACTAAACGGAAAACAATCGGTTTTTCCTTATCACGGGAGCAAAGAGATTGGTACAGGTTTAGTAAATAAGATTA
AGAAAGACTTAGATCTTAAATAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9281.56 Da Isoelectric Point: 5.1186
>AT199426 WP_003468816.1 NZ_CP072988:2344168-2344419 [Xanthomonas translucens pv. translucens]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE
Download Length: 252 bp
>AT199426 NZ_CP097339:c799820-799401 [Mannheimia haemolytica]
ATGTTACGCTACCCAGTTGAAATTACCCCTGATGATAACGGCACATATCTTGTGACTTGCCCTGATATTCCTGAAATGGC
AAGCGTAGGTGAGGACTTAGAAGAAGCCCTATTAGAAGCACAAGATGGCTTAGCCACAGCCCTTGAATTCTATTTTGATG
ATAGACGAGAAATACCAATGCCAAGCCCAATTAAAGAGGGACAACATACGGTTAATCTTACCGTGCTGCAATCAATGAAA
GTATTTCTCTTAAATGAAATGATTAAACAAGGTGTACGCAAAGCAGAAATGGCAAGACGATTAGATGTACACTTACCACA
GATAGATCGCCTATTAGATTTTAATCATTCCACAAAAGTAGAATTTGTTGAGAAAGCCTATGGTAAGCTAAATCAACACT
TTACTATTCTCCCTCACTAA
ATGTTACGCTACCCAGTTGAAATTACCCCTGATGATAACGGCACATATCTTGTGACTTGCCCTGATATTCCTGAAATGGC
AAGCGTAGGTGAGGACTTAGAAGAAGCCCTATTAGAAGCACAAGATGGCTTAGCCACAGCCCTTGAATTCTATTTTGATG
ATAGACGAGAAATACCAATGCCAAGCCCAATTAAAGAGGGACAACATACGGTTAATCTTACCGTGCTGCAATCAATGAAA
GTATTTCTCTTAAATGAAATGATTAAACAAGGTGTACGCAAAGCAGAAATGGCAAGACGATTAGATGTACACTTACCACA
GATAGATCGCCTATTAGATTTTAATCATTCCACAAAAGTAGAATTTGTTGAGAAAGCCTATGGTAAGCTAAATCAACACT
TTACTATTCTCCCTCACTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1C3TRG2 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1C3TRJ9 |