Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3843704..3843972 Replicon chromosome
Accession NZ_CP072980
Organism Escherichia coli strain 2547

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3843742..3843844 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3843704..3843972 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBW66_RS18840 3840862..3842301 + 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KBW66_RS18845 3842418..3842654 + 237 WP_001295499.1 YebV family protein -
KBW66_RS18850 3842759..3842950 + 192 WP_001296140.1 YebW family protein -
KBW66_RS18855 3842951..3843607 - 657 WP_000812745.1 protein-serine/threonine phosphatase -
- 3843704..3843972 + 269 - - Antitoxin
- 3843742..3843844 - 103 - - Toxin
KBW66_RS18860 3844002..3844343 - 342 WP_000976472.1 YebY family protein -
KBW66_RS18865 3844356..3845228 - 873 WP_000879317.1 copper homeostasis membrane protein CopD -
KBW66_RS18870 3845232..3845606 - 375 WP_000168747.1 CopC domain-containing protein YobA -
KBW66_RS18875 3845745..3845975 + 231 WP_000916763.1 DNA polymerase III subunit theta -
KBW66_RS18880 3846077..3846733 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
KBW66_RS18885 3846757..3847419 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T199376 NZ_CP072980:c3843844-3843742 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT199376 NZ_CP072980:3843704-3843972 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References