Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4140237..4140508 Replicon chromosome
Accession NZ_CP072976
Organism Escherichia coli strain EC2341

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4140367..4140470 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4140237..4140508 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBW65_RS19845 4136792..4137454 - 663 WP_000944256.1 exodeoxyribonuclease X -
KBW65_RS19850 4137478..4138134 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
KBW65_RS19855 4138236..4138466 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KBW65_RS19860 4138605..4138979 + 375 WP_000204699.1 CopC domain-containing protein YobA -
KBW65_RS19865 4138983..4139855 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
KBW65_RS19870 4139868..4140209 + 342 WP_000976492.1 YebY family protein -
- 4140237..4140508 - 272 - - Antitoxin
- 4140367..4140470 + 104 - - Toxin
KBW65_RS19875 4140605..4141261 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
KBW65_RS19880 4141262..4141453 - 192 WP_001296140.1 YebW family protein -
KBW65_RS19885 4141558..4141794 - 237 WP_001295499.1 YebV family protein -
KBW65_RS19890 4141912..4143351 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T199340 NZ_CP072976:4140367-4140470 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT199340 NZ_CP072976:c4140508-4140237 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References