Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2462430..2463113 Replicon chromosome
Accession NZ_CP072933
Organism Xylella fastidiosa subsp. multiplex strain AlmaEM3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KBP49_RS10755 Protein ID WP_004086858.1
Coordinates 2462430..2462858 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KBP49_RS10760 Protein ID WP_004086856.1
Coordinates 2462859..2463113 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBP49_RS10725 (KBP49_10725) 2458984..2459745 - 762 WP_004085598.1 Bax inhibitor-1/YccA family protein -
KBP49_RS10750 (KBP49_10750) 2460946..2462340 + 1395 WP_140161061.1 hypothetical protein -
KBP49_RS10755 (KBP49_10755) 2462430..2462858 - 429 WP_004086858.1 type II toxin-antitoxin system VapC family toxin Toxin
KBP49_RS10760 (KBP49_10760) 2462859..2463113 - 255 WP_004086856.1 hypothetical protein Antitoxin
KBP49_RS10765 (KBP49_10765) 2463238..2463780 + 543 WP_071870032.1 hypothetical protein -
KBP49_RS10770 (KBP49_10770) 2464101..2464474 - 374 Protein_2134 DUF596 domain-containing protein -
KBP49_RS10775 (KBP49_10775) 2464486..2464791 - 306 WP_228762248.1 DUF769 domain-containing protein -
KBP49_RS10780 (KBP49_10780) 2464990..2465382 - 393 WP_038211775.1 DUF596 domain-containing protein -
KBP49_RS10785 (KBP49_10785) 2465393..2465650 - 258 WP_021358680.1 hemagglutinin -
KBP49_RS10790 (KBP49_10790) 2465924..2466307 - 384 WP_004086848.1 DUF596 domain-containing protein -
KBP49_RS10795 (KBP49_10795) 2466312..2467349 - 1038 WP_140189438.1 DUF769 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15641.79 Da        Isoelectric Point: 5.1634

>T199229 WP_004086858.1 NZ_CP072933:c2462858-2462430 [Xylella fastidiosa subsp. multiplex]
MIVLDTNVVSEAMKPEPDAAVRTWLNEQMSVTLYLSSVTLSELLFGIAVLPTSKRKDMLARTLDGLLDLFNERVLPFDTD
AARHYAELAVKARNNGRGFPTPDGYIAAIAASRGYIVASRDTSAYESSGVQVINPWQYSKQT

Download         Length: 429 bp

>T199229 NZ_CP097248:c1720125-1719208 [Klebsiella pneumoniae]
ATGGATATACAGGCGCCTTATTATCGGCAGGTTGCTCTGCTAATGCAGGTTTTACCCTATGTTGCTGTCGAACGGGAATT
TGCGCTGAAAGGTGGCACTGCCATCAATCTCTTTATCCGCGATTTCCCTCGATTATCGGTGGATATCGACCTCGCCTGGG
TGCCCCTGGAAAGCAGAGCCATCGCTTTACCTCATATACGGGATGCGCTTGCACGTATTGCCGCCAATCTGCAACAACAG
GCAGGTATGAGCGCTGTATTACAAGCTAATCGTTCAGATGAGATGCGTGTCATTGTTACTACCGATAGCGCGCAAATAAA
GATAGAGGTTTCACCGGTCGCCCGGGGAACATTATATCCACCACAGGAGCGAGAAGTGGTGGGGGCGGTAGAGGACGTTT
TTGGCTATGCCAGCCTTCCAGTGGTTTCGTTGCCTGACCTCTACGGTGGAAAATTATGCGCGGCGCTGGATCGCCAGCAT
CCCAGAGATTTTTATGACGTGAAATTACTTCTTGATGCGCAGGAGCTTGACCGTCCCATTTTCAATGGGTTTATCGTGTA
TTTACTGAGCCATAATCGGCCTCTGGCTGAAGTGCTGAATCCTCGCTGGAAAGATATTGCTGAACCTTTTTACCGTGAAT
TCAGCGGGATGACATTTGAGACGATAGCCCTGGAGGAACTGACAGCAGTCCCCAACAGGATGATTGCTGCGTTAAAATCC
TGTTTCACACAACAGGATGTCGATTTTTTACTGTCATTTAAACGAGGCGAACCAGACTGGCGTTTAGCGCCGGAAATGCG
TATTCAGGATTTGCCTGCCGTGCAGTGGAAATTGCGCAATATTCATCAGATGCCAGCGATAAAACGCGCTGAGTCATTAG
ATAAACTGGAAAAGGTGCTGGCCGAGTGGCGCAGTTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9601.95 Da        Isoelectric Point: 6.4732

>AT199229 WP_004086856.1 NZ_CP072933:c2463113-2462859 [Xylella fastidiosa subsp. multiplex]
MAMLTVRNLPDEVHRALRVRAATHGRSTEAEVREILTNIVKPDERVRIGDALAILGREIGLNNEDFTTFDKVRDKTQAEP
MRFE

Download         Length: 255 bp

>AT199229 NZ_CP097248:c1720889-1720131 [Klebsiella pneumoniae]
ATGGCAACAAAATTAAACTGGCTGCTGCAAAACAGCGCTCCCGGAGATGTGATCCTTCAGTCCTGGTTAAGCCAGCATGC
CATCTCTCCCTCTCTGGCCTTTAAATACGCGCAAAGTGGCTGGTTAAAAAAAAGAGGCAACGGCGTATATGCGCGTGCGG
GACGTGAGCCGGAGTGGAACGATGCATTAGCATGTTTGCAAAATCAGCTTGCCGCTCCGGTGTATGTTGCGGGGCTCAGT
AGCTTAGTCTGGCAGGGCCGTTCACACTATCTACAGCTAAAACAAAACCAGTGCTGGCTTAGTGTGGAAAATAAAGCGCT
GCTGCCGAAATGGTTCAGGGAATTCCCGGGTGTGGAGTGGATAGTCATATCGGGGAAAAAACTGCCGGTGCTGGATGATA
GATACCGTGTAACGCTTGATATAAAAGGGAAAAAACTCATCGGCAGTGCGCCAGAACTGGCTGCTTACGAGTTGCTGAGC
GCGGTGCCGGGGACCCTCTCATTTAACCACGCTGCAGAGCTTTTCCAGGGGCTGGTTAATCTTAATCCTCGTAAAGTAGA
GTATCTTCTTTCCGTCAGCCAGTCCGTGCAGGCCAAGCGTTTGTATCTCTTCTTCGCCAGTTTTTACGAGCATGGCTGGC
TCAAACGAATCGATAGCCAAAAAATCGCTCTGGGAGCGGGCAAGCGGCAAATCGTGGAAAATGGAAAGTTCAATGCTCAA
TACCAAATCACAGTGCCTGAACGCTTTCAAAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References