Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pasABC/RelE-HTH |
| Location | 1350479..1350956 | Replicon | chromosome |
| Accession | NZ_CP072933 | ||
| Organism | Xylella fastidiosa subsp. multiplex strain AlmaEM3 | ||
Toxin (Protein)
| Gene name | pasB | Uniprot ID | - |
| Locus tag | KBP49_RS05850 | Protein ID | WP_004087087.1 |
| Coordinates | 1350690..1350956 (+) | Length | 89 a.a. |
Antitoxin (Protein)
| Gene name | pasA | Uniprot ID | A0A7G7TPD2 |
| Locus tag | KBP49_RS05845 | Protein ID | WP_004091377.1 |
| Coordinates | 1350479..1350706 (+) | Length | 76 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KBP49_RS05805 (KBP49_05805) | 1345606..1346751 | - | 1146 | WP_140160953.1 | baseplate J/gp47 family protein | - |
| KBP49_RS05810 (KBP49_05810) | 1346850..1347146 | + | 297 | WP_004089252.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| KBP49_RS05815 (KBP49_05815) | 1347150..1347455 | + | 306 | WP_038211623.1 | putative addiction module antidote protein | - |
| KBP49_RS05820 (KBP49_05820) | 1347466..1347819 | - | 354 | WP_071870030.1 | hypothetical protein | - |
| KBP49_RS05825 (KBP49_05825) | 1347816..1348457 | - | 642 | WP_071870029.1 | Gp138 family membrane-puncturing spike protein | - |
| KBP49_RS05830 (KBP49_05830) | 1348454..1349284 | - | 831 | WP_140160954.1 | hypothetical protein | - |
| KBP49_RS05835 (KBP49_05835) | 1349281..1349598 | - | 318 | WP_012382585.1 | hypothetical protein | - |
| KBP49_RS05840 (KBP49_05840) | 1349598..1350368 | - | 771 | WP_140160955.1 | hypothetical protein | - |
| KBP49_RS05845 (KBP49_05845) | 1350479..1350706 | + | 228 | WP_004091377.1 | DUF6290 family protein | Antitoxin |
| KBP49_RS05850 (KBP49_05850) | 1350690..1350956 | + | 267 | WP_004087087.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| KBP49_RS05855 (KBP49_05855) | 1350967..1352856 | - | 1890 | WP_140160956.1 | phage tail tape measure protein | - |
| KBP49_RS05860 (KBP49_05860) | 1353004..1353246 | - | 243 | WP_234499994.1 | putative phage tail assembly chaperone | - |
| KBP49_RS05865 (KBP49_05865) | 1353264..1353602 | - | 339 | WP_140160957.1 | hypothetical protein | - |
| KBP49_RS05870 (KBP49_05870) | 1353612..1354094 | - | 483 | WP_004090290.1 | hypothetical protein | - |
| KBP49_RS05875 (KBP49_05875) | 1354104..1355312 | - | 1209 | WP_140160989.1 | DUF2213 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1343801..1363808 | 20007 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 89 a.a. Molecular weight: 10207.80 Da Isoelectric Point: 10.3398
>T199227 WP_004087087.1 NZ_CP072933:1350690-1350956 [Xylella fastidiosa subsp. multiplex]
MAWTIDYTDTAKQQLRKLDKHMARRIVDFMDERIAGLENPRSSGKALTGPLGGFWRYRVGDFRVVCDIQDSVLRVLVVRV
GHRGEIYR
MAWTIDYTDTAKQQLRKLDKHMARRIVDFMDERIAGLENPRSSGKALTGPLGGFWRYRVGDFRVVCDIQDSVLRVLVVRV
GHRGEIYR
Download Length: 267 bp
>T199227 NZ_CP097248:c1459294-1458761 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA
Antitoxin
Download Length: 76 a.a. Molecular weight: 8615.63 Da Isoelectric Point: 5.0958
>AT199227 WP_004091377.1 NZ_CP072933:1350479-1350706 [Xylella fastidiosa subsp. multiplex]
MATSIRLSPEMEQRLNSLASHTGRTKAYYLREIIEHGIEEMEDYYLAADVLERVRHGQEQVHSAADVRKTLGLDD
MATSIRLSPEMEQRLNSLASHTGRTKAYYLREIIEHGIEEMEDYYLAADVLERVRHGQEQVHSAADVRKTLGLDD
Download Length: 228 bp
>AT199227 NZ_CP097248:c1459571-1459305 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|