Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 1069509..1070263 Replicon chromosome
Accession NZ_CP072933
Organism Xylella fastidiosa subsp. multiplex strain AlmaEM3

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag KBP49_RS04610 Protein ID WP_021358673.1
Coordinates 1069784..1070263 (+) Length 160 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag KBP49_RS04605 Protein ID WP_004085396.1
Coordinates 1069509..1069781 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBP49_RS04590 (KBP49_04590) 1065257..1067290 - 2034 WP_234545896.1 glycoside hydrolase family 3 protein -
KBP49_RS04595 (KBP49_04595) 1067518..1068136 - 619 Protein_904 IS607 family transposase -
KBP49_RS04600 (KBP49_04600) 1068252..1069157 + 906 WP_040123139.1 AEC family transporter -
KBP49_RS04605 (KBP49_04605) 1069509..1069781 + 273 WP_004085396.1 DUF1778 domain-containing protein Antitoxin
KBP49_RS04610 (KBP49_04610) 1069784..1070263 + 480 WP_021358673.1 GNAT family N-acetyltransferase Toxin
KBP49_RS04615 (KBP49_04615) 1070599..1071663 - 1065 WP_080654483.1 toprim domain-containing protein -
KBP49_RS10980 1071709..1071783 - 75 Protein_909 hypothetical protein -
KBP49_RS04620 (KBP49_04620) 1071758..1072756 - 999 WP_004085391.1 MBL fold metallo-hydrolase -
KBP49_RS04625 (KBP49_04625) 1072887..1073573 - 687 WP_071869569.1 TIGR02453 family protein -
KBP49_RS04630 (KBP49_04630) 1073570..1075006 - 1437 WP_071869568.1 exodeoxyribonuclease I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(33-146)

Antitoxin

Vibrio phage ICP1, Orf50

(3-85)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17645.42 Da        Isoelectric Point: 9.9283

>T199225 WP_021358673.1 NZ_CP072933:1069784-1070263 [Xylella fastidiosa subsp. multiplex]
MQISTPHSLTAAHRLDEFNCGEPSLDDWLKRRALTNHLNGASRTFVVIDANQYVLGYYALAAGAVAHQEATRAIRRNMPD
PVPVMVLGRLAVDTRAQGIKLGAALLKDTVTRVQSIAENAGVRALVVHALNERAKQFYEYYGFRASPMHLMTLMLPIKF

Download         Length: 480 bp

>T199225 NZ_CP097247:1974274-1974432 [Trueperella pyogenes]
GTGAAGATTCGGCAAACCGACGTGTATGCTCGCTGGTTTCGCAAGCTCAAAGATGTCCAGGGCAAGGCCCGAATCAATAT
TGCACTTCAGCGTTGCAAAATAGCTGGCGAAGTAGTGGGTGACGTCAAGCCGGTTGGTGATGGCGTTTTTGAGATGTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10264.77 Da        Isoelectric Point: 5.0488

>AT199225 WP_004085396.1 NZ_CP072933:1069509-1069781 [Xylella fastidiosa subsp. multiplex]
MRDASINLRAMPEQRDLIDQAANLLGKNRSDFMLEAACERAKAIILDQVFFNLDEERFRQFTVLLNAPQDTNPGLNRLMA
IKAPWSISNT

Download         Length: 273 bp

>AT199225 NZ_CP097247:1974579-1974872 [Trueperella pyogenes]
ATGGGAGTAAAAATCAGCACCTGGGATGCCAGCGAATACCTTGAAACCAAGGAAGATATTGCTGCCTACCTGAACGCGGC
ACTCGAAGAGGGCGACCCGGCTCTCCTGCAGGTCGCACTTGGTGATGTCGCCAAAGCGCGTGGTGTGACCGCTATCGCGC
GAGAAGCCGGTGTTGGACGCGAGTCTCTCTACAAGTCGCTTTCCGAAAACGGCAATCCGTCCTGGCAGACCATCACAAAG
GTTCTCACTGCACTCGGGCTGAAGATCGAAGTCAAAGCCATTGCGTTAGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References